| Yazarlar |
Sibel Çelik
|
|
Senay Yurdakul
|
Prof. Dr. Belgin ERDEM
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| In the present work, a newly synthesized silver(I) complex was characterized using elemental analysis, UV–Vis spectroscopy, and infrared spectroscopy. DFT calculations at the B3LYP/LANL2DZ level were used to investigate structural, electronic, and spectroscopic properties. The intermolecular interactions in the structure were analyzed by topological AIM, RDG, and NBO approaches. Compound [Ag(4-pyridinecarboxaldehyde)4]NO3 proved to be the most active compound in this study and showed the highest antibacterial activity against S. aureus ATCC 29,213, S. epidermidis ATCC 35,984 and P. aeruginosa ATCC 27,853. Test compound was examined for antiquorum-sensing activity against C. violaceum ATCC 12,472 and title compound exhibited good antiquorum-sensing activity. In addition, these compound activity relationships were further supported by in-silico molecular docking studies where some of the active title compound showed maximum dock score. |
| Anahtar Kelimeler |
| 4-pyridinecarboxaldehyde | AIM | Antibacterial | Antiquorum-sensing | DFT | Molecular docking |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Elsevier BV |
| Dergi ISSN | 0022-2860 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2022 |
| Cilt No | 1261 |
| Sayı | 1 |
| Sayfalar | 132902 / 0 |
| Doi Numarası | 10.1016/j.molstruc.2022.132902 |
| Makale Linki | http://dx.doi.org/10.1016/j.molstruc.2022.132902 |
| Atıf Sayıları | |
| SCOPUS | 13 |
