Predictive Performance of Triglyceride-Glucose Index on Asymptomatic Multiple Organ Damage in Patients with Newly Diagnosed Hypertension
Yazarlar (2)
Dr. Öğr. Üyesi Ahmet Kıvrak Hacettepe Üniversitesi, Türkiye
Dr. Öğr. Üyesi Alp YILDIRIM Kırşehir Ahi Evran Üniversitesi, Türkiye
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Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Revista de Investigación Clínica (Q2) | ||
| Dergi ISSN | 0034-8376 Dergi Bilgileri (2023) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 09-2023 |
| Cilt / Sayı / Sayfa | 75 / 5 / 221–232 | DOI | 10.24875/RIC.23000113 |
| Makale Linki | https://doi.org/10.24875/ric.23000113 | ||
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Kardiyoloji
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| Özet |
| KIVRAK, Ahmet y YILDIRIM, Alp. Predictive Performance of Triglyceride-Glucose Index on Asymptomatic Multiple Organ Damage in Patients with Newly Diagnosed Hypertension. Rev. invest. clín.[online]. 2023, vol. 75, n. 5, pp. 221-232. Epub 12-Mar-2024. ISSN 2564-8896. https://doi. org/10.24875/ric. 23000113.Background:Insulin resistance (IR) contributes to the development of hypertension and mediated organ damage (HMOD) through various mechanisms.Objectives:The objective of the study was to assess the diagnostic performance of the triglyceride-glucose (TyG) index, a surrogate marker of IR, in predicting the presence and severity of HMOD in newly diagnosed untreated hypertensive patients from an academic training and research hospital.Methods:The study included 438 patients with newly diagnosed, untreated hypertension. The control group comprised normotensive individuals matched on a 1: 1 ratio based on age, gender, body mass index, and smoking using the nearest neighbor method. The presence of HMOD was defined by renal damage (microalbuminuria> 30 mg/day or proteinuria> 150 mg/day), vascular damage (carotid intima-media thickness> 0.9 mm or presence of plaque), or cardiac damage (left ventricular mass index> 95 g/m2 in women and> 115 g/m2 in men). The severity of HMOD was considered as single-, two-, or triple-organ damage.Results:TyG index values were higher in the hypertensive group than the normotensive group. An increased TyG index was independently associated with HMOD (OR: 1.33, p< 0.001). The TyG index exhibited gradually increasing threshold values for distinguishing patients … |
| Anahtar Kelimeler |
| Atherosclerosis | Hypertensive organ damage | Insulin resistance | Triglyceride-glucose index |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 3 |