Synthesis, single crystal investigations, DFT studies, biological activities, DNA cytotoxicity and molecular docking studies of copper(II) complex derived from the new o-vanillin Schiff base ligand
Yazarlar (6)
Nuray Şenyüz Öztürk Kirsehir Ahi Evran University
Doç. Dr. Murat ÇINARLI Kırşehir Ahi Evran Üniversitesi, Türkiye
Çiğdem Yüksektepe Ataol Cankiri Karatekin University, Türkiye
Celal Tuğrul Zeyrek Cankiri Karatekin University, Türkiye
Doç. Dr. Esin KIRAY Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ayşe Nur COŞKUN DEMİRKALP Kırşehir Ahi Evran Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | POLYHEDRON (Q2) | ||
| Dergi ISSN | 0277-5387 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2025 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 267 / 1 / 117315–0 | DOI | 10.1016/j.poly.2024.117315 |
| Makale Linki | https://doi.org/10.1016/j.poly.2024.117315 | ||
| Özet |
| A novel Schiff base derivative,(E)-N’-(2-hydroxy-3-methoxybenzylidene)-2-phenylacetohydrazide (HMPH, H 2 L), and its Cu (II) complex were synthesized through the direct condensation of o-vanillin with phenylacetichydrazide in ethanol under reflux conditions. The synthesized ligand was identified using elemental analysis, Fourier transform infrared (FTIR) and ultraviolet–visible (UV–Vis.) spectroscopy. The structures of HMPH (C 16 H 16 N 2 O 3) 2 and its Cu (II) complex [Cu (L)(H 2 O)]· H 2 O (C 16 H 16 N 2 CuO 4· H 2 O) were analysed by single crystal X-ray diffraction technique. The X-ray diffraction results showed that HMPH crystallised in an orthorhombic Pca 2 1 space group with a Z value of 8, while [Cu (L)(H 2 O)]· H 2 O crystallised in a monoclinic C 2/c space group with the same z value. The Cu (II) ion is coordinated to the acetohydrazide ligands via hydrazone nitrogen, aceto oxygen (N (2) and O (1 … |
| Anahtar Kelimeler |
| anti-biofilm | Copper complex | Molecular docking | o-vanillin Schiff base | X-ray |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 8 |
| Web of Science | 8 |