Chemical profiling and biological activity evaluation of propolis from Çayeli-Rize, Eastern Black Sea Region, Anatolia
Yazarlar (8)
Gazi University, Türkiye
Gazi University, Türkiye
Hacettepe University, Türkiye
Gazi University, Türkiye
Suleyman Demirel University, Türkiye
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Gazi University, Türkiye
Zonguldak Bulent Ecevit University, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | NATURAL PRODUCT RESEARCH (Q3) | ||
| Dergi ISSN | 1478-6419 Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2024 |
| Cilt / Sayı / Sayfa | 0 / 0 / – | DOI | 10.1080/14786419.2024.2443500 |
| Makale Linki | https://figshare.com/articles/journal_contribution/Chemical_profiling_and_biological_activity_evaluation_of_propolis_from_ayeli-Rize_Eastern_Black_Sea_Region_Anatolia/28070274 | ||
| Özet |
| The constituents of the aqueous, ethanol, hexane, and methanol extracts of Anatolian propolis collected from the Eastern Black Sea Region (& Ccedil;ayeli-Rize) were investigated by GC-MS, HPLC and AAS. Interestingly, lactulose has been identified. Ten phenolic compounds, namely caffeic acid, ferulic acid, rutin, taxifolin, quercetin, kaempferol, apigenin, silicristin, silibinin and gallic acid were determined. The contents of phenolic acids and flavonoids varied between 17.04-642.59 and 1.18-2749.20 ppm, respectively. Minerals found in propolis were Na, K, Ca, Mg and Zn. The methanol extract had the highest antiproliferative activity against the A549 cell line with an IC50 value of 0.1821 mu L/mL. The extracts showed higher antibacterial activity against Gram-negative bacteria compared to Gram-positive bacteria. |
| Anahtar Kelimeler |
| Propolis | chemical composition | flavonoids | antiproliferative activity | antibacterial activity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |