| Yazarlar |
Ali Disli
|
|
Nurdan Akdogan
|
|
Selinay Ozel
|
|
Levent Nuralin
|
|
Senem Akkoc
|
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Dogukan Doyduk
|
|
Gulay Dilek
|
| Özet |
| The constituents of the aqueous, ethanol, hexane, and methanol extracts of Anatolian propolis collected from the Eastern Black Sea Region (& Ccedil;ayeli-Rize) were investigated by GC-MS, HPLC and AAS. Interestingly, lactulose has been identified. Ten phenolic compounds, namely caffeic acid, ferulic acid, rutin, taxifolin, quercetin, kaempferol, apigenin, silicristin, silibinin and gallic acid were determined. The contents of phenolic acids and flavonoids varied between 17.04-642.59 and 1.18-2749.20 ppm, respectively. Minerals found in propolis were Na, K, Ca, Mg and Zn. The methanol extract had the highest antiproliferative activity against the A549 cell line with an IC50 value of 0.1821 mu L/mL. The extracts showed higher antibacterial activity against Gram-negative bacteria compared to Gram-positive bacteria. |
| Anahtar Kelimeler |
| Propolis | chemical composition | flavonoids | antiproliferative activity | antibacterial activity |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | NATURAL PRODUCT RESEARCH |
| Dergi ISSN | 1478-6419 |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 12-2024 |
| Doi Numarası | 10.1080/14786419.2024.2443500 |
| Atıf Sayıları |
