| Yazarlar (1) |
Dr. Öğr. Üyesi Selcen DURAN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Erer-Özbek S, Yapıcı Z, Tüzün E, Giriş M, Duran S, Taşkapılıoğlu Ö, Okan M. A case of hyperkinetic movement disorder associated with LGI1 antibodies. Turk J Pediatr 2015; 57: 514-517.Encephalitis associated with leucine-rich glioma inactivated 1 (LGI1) antibodies is often encountered in elderly male patients and may infrequently present with isolated syndromes. A 6-year-old boy was admitted with acute onset severe oral and facial stereotypic and choreiform movements. On his neurologic examination, he had repetitive and rhythmic movements in orolingual muscles including tongue protrusion, limb chorea and minimal facial stereotypic movements. Anti-streptolysin O (ASO) titers were found severely elevated in several measurements. Well-characterized antibodies against ion channels and synapse proteins were negative whereas LGI1 antibody was positive in both serum and CSF. Marked clinical improvement was observed after immunotherapy. Here, we present the first pediatric case with LGI1 antibody associated hyperkinetic movement disorders and emphasize the importance of investigating neuronal autoantibodies in patients with isolated and treatment resistant movement disorders |
| Anahtar Kelimeler |
| hyperkinetic movement | autoimmune encephalitis | LGI1 antibody | Sydenham's chorea | immunoglobulin therapy |
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | TURKISH JOURNAL OF PEDIATRICS |
| Dergi ISSN | 0041-4301 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | Türkçe |
| Basım Tarihi | 01-2015 |
| Cilt No | 57 |
| Sayı | 5 |
| Sayfalar | 4 / 517 |
| Makale Linki | https://turkjpediatr.org/article/view/1277/1270 |
