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Optimal Cut-Off Scores of Performance-Based Tests of Physical Function to Discriminate Disease Severity in Patients with Knee Osteoarthritis   
Yazarlar
Gulsah OZSOY
Muhammed KODAK
Caner KARARTI
Fatih OZYURT
Seyde KODAK
Basak KARACAY
Ismail OZSOY
Özet
Background A set of physical tests representing typical activities relevant to persons with knee osteoarthritis (KOA) is recommended by the Osteoarthritis Research Society International (OARSI). The objective of this study was to designate the cut-off values for OARSI-recommended performance-based tests to better discriminate disease severity in patients with KOA. Methods As recommended by the OARSI, we conducted the 30-s Chair Stand Test (30s-CST), 40m Fast-Paced Walk Test (40m FPWT), Stair Climb Test (SCT), six-Minute Walk Test (6MWT), and Timed Up and Go test (TUG). To investigate the discriminative power of the performance test scores using the Kellgren and Lawrence (KL) grading system, receiver operating characteristic (ROC) curve analysis was performed. It was used Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) to assess self-administered health status. Results Forty-eight patients with bilateral KOA were included this study. The area under the curves for four of the five performance tests (30s-CST, 6-step SCT, 40m FPWT, and TUG) had acceptable discrimination (0.753 to 0.793), while the 6MWT had excellent discrimination (0.860). The stepwise multiple regression analysis demonstrated that 6MWT and 30s-CST were significant and independent determinants of WOMAC score, explaining 48% of the variance (p< 0.001). Conclusion It can be concluded that the OARSI performance tests can discriminate disease severity in individuals with KOA. The 6MWT has the highest level of discriminative validity among all. In addition, despite the correlation between all five tests and the WOMAC score ...
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Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü Uluslararası alan indekslerindeki dergilerde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı Available at SSRN 4896673
Dergi Tarandığı Indeksler
Makale Dili İngilizce
Basım Tarihi 01-2024
BM Sürdürülebilir Kalkınma Amaçları
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