| Yazarlar (5) |
Dilek Nartop
Düzce Üniversitesi, Türkiye |
|
Elvan Hasanoğlu Özkan
Gazi Üniversitesi, Türkiye |
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Nurdan Kurnaz Yetim
Kırklareli Üniversitesi, Türkiye |
|
İnci Özdemir
|
| Özet |
| In this paper, eight novel α-N-heterocyclic thiosemicarbazone complexes were synthesized in search of new biologically active compounds, and characterized organic elemental analysis, nuclear magnetic resonance spectroscopy, infrared spectra, thermogravimetric analysis, ultraviolet-visible spectroscopy, molar conductance and magnetic susceptibility measurements. The antimicrobial activity of these complexes was examined against ten disease-causing pathogens: Gram-positive bacteria ( ATCC9341, ATCC12228, RSKK863) and Gram-negative bacteria ( ATCC27853, ATCC27853, ATCC51342, H NCTC9018394, NCTC2966, RSKK96026) and yeast ( Y-1200-NIH). The results revealed that the α-N-heterocyclic thiosemicarbazone compounds showed potent activity. It was observed that all thiosemicarbazone complexes were more susceptible to Gram-negative strains based on the presence of an electron-withdrawing substituent (-Br/-Cl/-F). It was determined that thiosemicarbazone Cucomplexes showed stronger antifungal effects. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | RSC Advances |
| Dergi ISSN | ISSN-2046 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 09-2024 |
| Cilt No | 14 |
| Sayı | 40 |
| Sayfalar | 29308 / 29318 |
| Doi Numarası | 10.1039/d4ra04002c |
| Atıf Sayıları | |
| WoS | 4 |
