Synthesis, Antimicrobial, and DNA-Binding Evaluation of Novel Schiff Bases Containing Tetrazole Moiety And Their Ni(II) and Pt(II) Complexes
Yazarlar (5)
Merve Ulular
Nurşen Sarı Gazi Üniversitesi, Türkiye
Fatma Han
Prof. Dr. Hatice ÖĞÜTCÜ Kırşehir Ahi Evran Üniversitesi, Türkiye
Elvan Hasanoğlu Özkan Gazi Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı PHARMACEUTICAL CHEMISTRY JOURNAL (Q4)
Dergi ISSN 0091-150X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2024
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 57 / 10 / 1609–1620 DOI 10.1007/s11094-024-03056-7
Özet
Ni(II) and Pt(II) complexes of tetrazole-containing Schiff bases were synthesized and characterized by physicochemical and various spectroscopic studies. To examine its potential as a candidate anticancer drug, the binding properties of ct-DNA were investigated. The characteristic binding constant (Kb) and binding mode of the complexes with calf th...
Anahtar Kelimeler
Schiff bases | tetrazole | Pt(II) complexes | calf thymus DNA | antimicrobial activity | pathogen microorganisms