| Yazarlar (6) |
Handan Tanyıldızı Kökkülünk
Türkiye |
|
Mustafa Demir
İstanbul Üniversitesi-Cerrahpaşa, Türkiye |
|
Ayşe Karadeniz Yıldırım
İstanbul Aydın Üniversitesi, Türkiye |
|
Suat Özkorucuklu
İstanbul Üniversitesi, Türkiye |
|
Baki Akkuş
Türkiye |
|
Doğan Yaşar
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| The 90Y microsphere treatment is emerging as a promising treatment modality in the management of patients with liver cancer. In treatment, microspheres are selectively infused into an affected hepatic region by transarterial catheterization. Microspheres that reach the tumor microcirculation use beta emission to destroy the tumor. The half-life of 90Y is 64.2 h and it decays to 90Zr. It emits high energy beta particles (max. 2.27 MeV, average 0.9 MeV) that have an average tissue penetration of 2.5 mm and a maximum penetration of 11 mm [1]. Considering high energy of particles emitted from 90Y, the patient-specific radiation dosimetry is very important to ensure radiation safety. All the dosimetric methods serve to address the same problems, such as determining the amount of activity to be administered to patients, checking the accuracy and reliability of treatment applications and determining the absorbed doses (AD) of irradiated tissues or organs after treatment. The radiation dosimetry of radiopharmaceuticals used for treatment in nuclear medicine clinics has been described in different ways as the determination of the absorbed dose per injected activity [2] or the calculation of the energy absorbed in tissue as a result of the energetic emission of radioactive atoms [3].Phantoms with characteristics similar to patients’ anatomy are used as the basis for dosimetry studies. The most effective way to model these phantoms is to use simple geometric shapes such as spheres, cubes and cylinders to define patients’ anatomy [4]. For simple geometric shapes, it is easy to calculate the absorbed dose analytically but when the geometry becomes more … |
| Anahtar Kelimeler |
| radionuclide dosimetry | Monte Carlo method | GATE | Y-90 |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | ACTA PHYSICA POLONICA A |
| Dergi ISSN | 1898-794X Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2020 |
| Cilt No | 138 |
| Sayı | 6 |
| Sayfalar | 801 / 808 |
| Doi Numarası | 10.12693/APhysPolA.138.801 |
| Makale Linki | http://przyrbwn.icm.edu.pl/APP/PDF/138/app138z6p08.pdf |
| Atıf Sayıları | |
| WoS | 3 |
| Google Scholar | 3 |
| Google Scholar | 3 |
