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Investigation of SNPs in BMP15 and GDF9 genes in “Çepni” and “Of” sheep in the Black Sea region of Turkey    
Yazarlar (1)
Doç. Dr. Koray KIRIKÇI Doç. Dr. Koray KIRIKÇI
Kırşehir Ahi Evran Üniversitesi, Türkiye
Devamını Göster
Özet
Sheep fertility genes have been studied in Turkey for many years. But so far it cannot be said that a satisfactory result has been achieved in terms of the number of detected polymorphisms on fertility genes. Exhibiting the genetic structure of local gene resources adapted to a particular region is very important for sustainability, conservation and breeding studies, and many other issues such as profitability. Therefore, the primary aim of this study was to investigate the single nucleotide polymorphisms (SNPs) on the BMP15 and GDF9 genes in two new Turkish sheep breeds, Çepni and Of. DNA sequencing was performed to identify SNPs in both genes of Çepni and Of sheep. One novel SNP (T755C) in the BMP15 gene and five known SNPs (c471C > T (G2), c477 G > A (G3), c721 G > A (G4), c978 A > G (G5), and c994 G > A (G6)) in the GDF9 gene, and a total of six SNPs were identified. Çepni and Of breeds showed a highly polymorphic structure for the genes examined. This finding shows that these two sheep breeds have great potential for future association studies. As a conclusion, the findings of this study were the first for the Çepni and Of breeds, and it should be examined for novel and other SNPs for more convincing results, especially litter size association studies, in new and other native sheep breeds in Turkey.
Anahtar Kelimeler
BMP15 | GDF9 | Of sheep | SNP | T755C | Çepni sheep
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Turkish Journal of Veterinary and Animal Sciences
Dergi ISSN 1300-0128
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2023
Cilt No 47
Sayı 3
Sayfalar 293 / 300
Doi Numarası 10.55730/1300-0128.4296