Sialic Acid-Functionalized Gold Nanoparticles for Sensitive and Selective Colorimetric Determination of Serotonin
Yazarlar (4)
Begüm Avcı Middle East Technical University (Metu), Türkiye
Dr. Öğr. Üyesi Yeliz AKPINAR Kırşehir Ahi Evran Üniversitesi, Türkiye
Gülay Ertaş Middle East Technical University (Metu), Türkiye
Mürvet Volkan
Middle East Technical University (Metu), Türkiye
Middle East Technical University (Metu), Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | ACS Omega (Q2) | ||
| Dergi ISSN | 2470-1343 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2024 |
| Cilt / Sayı / Sayfa | 9 / 22 / 23832–23842 | DOI | 10.1021/acsomega.4c01859 |
| Makale Linki | https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c01859 | ||
| UAK Araştırma Alanları |
Analitik Kimya
Nanoteknoloji
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| Özet |
| We present a novel colorimetric method inspired by nature’s complex mechanisms, capable of selectively determining serotonin with high sensitivity. This method exploits the inherent binding affinity of serotonin with sialic acid (SA) molecules anchored to gold nanoparticles (SA-AuNPs). Upon serotonin binding, SA-AuNPs aggregate, and a characteristic red shift in the absorbance of SA-AuNPs accompanied by a dramatic color change (red to blue) occurs, readily observable even without instrumentation. The proposed method effectively eliminates interventions from potential interfering species such as dopamine, epinephrine, l-tyrosine, glucosamine, galactose, mannose, and oxalic acid. The absence of a color change with l-tryptophan, a structurally related precursor of serotonin, further confirms the high selectivity of this approach for serotonin detection. The colorimetric method has a wide linear dynamic range (0 … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 11 |
| Scopus | 11 |
| Google Scholar | 11 |