| Yazarlar |
Cansın Medin Ceylan
Türkiye |
|
Tuğba Şahbaz
Türkiye |
Başak ÇİĞDEM KARAÇAY
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Background Platelet-rich plasma (PRP) and prolotherapy (PRL) are regenerative treatment approaches in the knee osteoarthritis (KOA). Aim To see how efficient PRP and PRL are in treating KOA. Methods A total of 108 patients with a diagnosis of KOA who received either PRL, PRP, or exercise therapy and whose 3-month follow-up data were available were included in this retrospective study (PRL n = 35 or PRP n = 35, exercise n = 38). Visual Analogue Scale (VAS) and The Western Ontario McMaster University Osteoarthritis Index (WOMAC) were used as outcome measures at baseline, 1 month, and 3 months. Results There were no statistically significant differences between the three groups in terms of demographic parameters, baseline assessments of pain intensity, or WOMAC scores. At the first and third months, all groups showed a substantial improvement in the VAS activity, resting and WOMAC values as compared to before treatment (p < 0.05). When the groups were compared, the VAS activity, resting, and WOMAC values in PRP and PRL improved significantly in the first and third months compared to the exercise group. At one month, there was a statistically significant improvement in VAS activity and WOMAC pain and total scores compared to PRP and PRL, but this improvement was not significant at 3 months. Conclusion Pain and disability were significantly improved with PRL and PRP compared with exercise therapy. Although PRP is more effective than PRL in the first month after treatment, PRL may be preferred due to its low cost, long-term efficacy, and low complication rates due to the periarticular application. |
| Anahtar Kelimeler |
| Knee osteoarthritis | Platelet-rich plasma | Prolotherapy |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Irish Journal of Medical Science |
| Dergi ISSN | 0021-1265 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | İngilizce |
| Basım Tarihi | 02-2023 |
| Cilt No | 192 |
| Sayı | 1 |
| Sayfalar | 193 / 198 |
| Doi Numarası | 10.1007/s11845-022-03168-7 |
| Makale Linki | http://dx.doi.org/10.1007/s11845-022-03168-7 |
| Atıf Sayıları | |
| WoS | 1 |
| SCOPUS | 2 |
| Google Scholar | 6 |
