| Yazarlar (6) |
Sibel Cevizci
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
|
Meliha Merve Hız
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
|
Sevilay Kılıç
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
|
Başak Büyük
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
|
Halil İbrahim Taş
Çanakkale Onsekiz Mart Üniversitesi, Türkiye |
Prof. Dr. Ülken Tunga BABAOĞLU
Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Toxoplasma gondii infection generally causes flu-like symptoms in healthy individuals; however, immunosuppression of the infected individual causes reactivation of the pathogen to its active form and relapse of the toxoplasmosis. Today it is known that toxoplasmosis triggers psychiatric disorders such as schizophrenia as well as behavioral changes such as suicide attempts. Although dermatological manifestations are very rare, the dermatological lesions are not unique. In addition, previous toxoplasma infection also causes congenital infections because of placental infection and causes birth defects and spontaneous abortion. T. gondii strains are mainly divided into three main clonal lineages, yet higher recombination rate causes unusual population structure and heterogeneous distribution of the pathogen. Both genetic variations, of the pathogen and the patients, are important for virulence property and success of the therapies. The scientist focuses on the genetic variations of the pathogens and individuals to achieve effective treatment and developed tailor-made medicines. Thus, understanding the molecular basis of the disease and the link of molecular mechanism with host immunity is important to fully know the disease and related disorders. In this chapter, we would like to evaluate the current knowledge on genetic, molecular characteristics of toxoplasmosis in view of public health genomics. |
| Anahtar Kelimeler |
| Kitap Adı | Toxoplasmosis |
| Bölüm(ler) | Toxoplasmosis and public health genomics |
| Kitap Türü | Kitap Bölümü |
| Kitap Alt Türü | Alanında uluslararası yayınlanan kitap bölümü |
| Kitap Niteliği | Diğer uluslararası bilimsel kitap |
| Kitap Dili | İngilizce |
| Basım Tarihi | 01-2017 |
| ISBN | 978-953-51-3269-1 |
| Basıldığı Ülke | Hırvatistan |
| Basıldığı Şehir | Rijeka |
