The Magnetic Nanobased Strategies to Overcome Drug Resistance in Breast Cancer Therapy (Handbook of Nanomaterials for Industrial Applications, Micro and Nano Technologies)
Yazarlar (2)
Prof. Dr. Serap YALÇIN AZARKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
Ufuk Gündüz
Middle East Technical University, Türkiye
Middle East Technical University, Türkiye
| Bölüm Adı | The Magnetic Nanobased Strategies to Overcome Drug Resistance in Breast Cancer Therapy | ||
| Kitap Adı | Handbook of Nanomaterials for Industrial Applications, Micro and Nano Technologies | ||
| Bölüm Sayfaları | 577-586 | ||
| Kitap Türü | Kitap Bölümü | ||
| Kitap Alt Türü | Alanında uluslararası yayınlanan kitap bölümü | ||
| Kitap Niteliği | Web of Science Core Collection indeksinde taranan bilimsel kitap | ||
| Kitap Dili | İngilizce | Basım Tarihi | 01-2018 |
| DOI Numarası | 10.1016/B978-0-12-813351-4.00033-X | ISBN | 9780128133521 |
| Basıldığı Ülke | Basıldığı Şehir | ||
| Özet |
| In cancer, multidrug resistance occurs due to alteration of drug targets, expression of drug efflux pump, and detoxification mechanisms, leading to reduced apoptosis and increased ability to repair DNA damage. The conventional treatment shows some limits, such as toxicity, lack of specificity, poor drug accumulation in tumor tissue, and severe side effects. Furthermore, the blood–brain barrier has a key role in limiting strategies of therapy, because anticancer drugs have little or no solubility to pass through this barrier. Therefore, alternative diagnostic and therapeutic approaches are needed in the era of novel drugs. Nanotechnology is considered the epitome of the emerging technologies that will have an important role in biomedical and pharmaceuticals industry. Governments and industry have spent millions of dollars on the research and development of nanobased biomaterials. After long and intensive studies … |
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BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 5 |
| Web of Science | 1 |