| Yazarlar |
F Sayir
|
|
Servet Kavak
Muğla Sıtkı Koçman Üniversitesi, Türkiye |
|
İsmail Meral
Bezm-İ Âlem Vakıf Üniversitesi, Türkiye |
|
Halit Demir
Yüzüncü Yıl Üniversitesi, Türkiye |
|
Prof. Dr. Nureddin CENGİZ
Sakarya Üniversitesi, Türkiye |
| Özet |
| Introduction: In this study we investigated the effect of crush and axotomy of phrenic nerves on oxidative stress and antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Results: The malondialdehyde level increased in diaphragm muscles after both crush and axotomy. The antioxidant enzymes, such as superoxide dismutase, glutathione peroxidase, carbonic anhydrase, and catalase, decreased in diaphragm muscles after both crush and axotomy. Conclusions: Crushing or axotomizing the phrenic nerves may produce oxidative stress in the diaphragm muscle of the rat by increasing lipid peroxidation and decreasing antioxidant enzyme activities. Muscle Nerve, 2012 |
| Anahtar Kelimeler |
| antioxidant enzyme | diaphragm muscle | oxidative stress | phrenic nerve degeneration | rat |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | MUSCLE & NERVE |
| Dergi ISSN | 0148-639X |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 03-2012 |
| Cilt No | 45 |
| Sayı | 3 |
| Sayfalar | 412 / 415 |
| Doi Numarası | 10.1002/mus.22312 |
| Makale Linki | http://doi.wiley.com/10.1002/mus.22312 |
| Atıf Sayıları | |
| WoS | 5 |
