| Yazarlar |
Servet Kavak
Muğla Sıtkı Koçman Üniversitesi, Türkiye |
|
M F Garca
|
|
I Gecit
|
|
İsmail Meral
Bezm-İ Âlem Vakıf Üniversitesi, Türkiye |
|
Prof. Dr. Nureddin CENGİZ
Sakarya Üniversitesi, Türkiye |
|
Halit Demir
Yüzüncü Yıl Üniversitesi, Türkiye |
| Özet |
| Introduction: This study was designed to assess the effect of extracorporeal shock-wave lithotripsy (ESWL) exposure of the parotid gland on oxidative stress and some trace element levels in the facial nerves of rats. Methods: Twelve male Wistar albino rats were divided into two groups, each consisting of 6 animals. The rats in the first group served as controls. The left parotid glands of animals in the second group were treated with 1000 18-kV shock waves while anesthetized with ketamine. The animals in both groups were euthanized 72 h after the ESWL treatment, and the right facial nerve was harvested for determination of oxidant/antioxidant status and trace element levels. Results: Lipid peroxidation product malondialdehyde (MDA) and antioxidant glutathione (GSH) levels increased, and the activities of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), decreased in the facial nerves of ESWL-treated rats. The levels of iron, lead, manganese, and cobalt increased, and magnesium, cadmium, and copper levels decreased. Conclusions: ESWL treatment of the parotid gland may increase lipid peroxidation and decrease antioxidant enzyme activity in adjacent tissues such as the facial nerve. It also causes a decrease or increase in many mineral levels of the facial nerve, which is an undesirable condition for normal physiological function. Muscle Nerve, 2012 |
| Anahtar Kelimeler |
| ESWL | facial nerve | oxidative stress | rat | trace element levels |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | MUSCLE & NERVE |
| Dergi ISSN | 0148-639X |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2012 |
| Cilt No | 45 |
| Sayı | 4 |
| Sayfalar | 562 / 566 |
| Doi Numarası | 10.1002/mus.22326 |
| Makale Linki | http://doi.wiley.com/10.1002/mus.22326 |
| Atıf Sayıları | |
| WoS | 4 |
