Synthesis, Antimicrobial, and DNA-Binding Evaluation of Novel Schiff Bases Containing Tetrazole Moiety And Their Ni(II) and Pt(II) Complexes
Yazarlar (5)
Merve Ulular
Prof. Dr. Nurşen Sarı Gazi Üniversitesi, Türkiye
Fatma Han
Prof. Dr. Hatice ÖĞÜTCÜ Kırşehir Ahi Evran Üniversitesi, Türkiye
Doç. Dr. Elvan Hasanoğlu Özkan Gazi Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı PHARMACEUTICAL CHEMISTRY JOURNAL (Q4)
Dergi ISSN 0091-150X Dergi Bilgileri (2024)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2024
Cilt / Sayı / Sayfa 57 / 10 / 1609–1620 DOI 10.1007/s11094-024-03056-7
UAK Araştırma Alanları
Mikrobiyoloji Bakteriyoloji
Özet
Ni(II) and Pt(II) complexes of tetrazole-containing Schiff bases were synthesized and characterized by physicochemical and various spectroscopic studies. To examine its potential as a candidate anticancer drug, the binding properties of ct-DNA were investigated. The characteristic binding constant (Kb) and binding mode of the complexes with calf th...
Anahtar Kelimeler
Schiff bases | tetrazole | Pt(II) complexes | calf thymus DNA | antimicrobial activity | pathogen microorganisms