| Yazarlar |
H Yüksek
|
|
M Alkan
|
|
Z Ocak
|
|
U Bahçeci
|
Öğr. Gör. Muhammet OCAK
Kırşehir Ahi Evran Üniversitesi |
|
M Özdemir
|
| Özet |
| 3-Alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 2 react with acyl halides such as chloroacetyl chloride, dichloroacetyl chloride and isobutyryl chloride to give the corresponding 3-alkyl(aryl)-4-chloroacetylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones 3, 3-alkyl(aryl)-4-(dichloroacetylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 4 and 3-alkyl(aryl)-4-isobutyrylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones 5, respectively. The newly synthesized compounds have been characterized by elemental analyses, IR, H-1 NMR, C-13 NMR and UV spectral data. In addition, all ten new compounds are titrated potentiometrically with tetrabutylammonium hydroxide in four different non-aqueous solvents such as isopropyl alcohol, tert-butyl alcohol, acetonitrile and N,N-dimethylformamide. The half neutralization potential values and the corresponding pK(a) values have been determined for all the cases. Thus, the effects of solvents and molecular structure upon acidity are investigated. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY |
| Dergi ISSN | 0376-4699 |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 07-2004 |
| Cilt No | 43 |
| Sayı | 7 |
| Sayfalar | 1527 / 1531 |
