The estimation of pore size distribution of electroporated MCF-7 cell membrane
Yazarlar (3)
Meriç Arda Eşmekaya Gazi Üniversitesi, Türkiye
Dr. Öğr. Üyesi Güney GÜRSOY Kırşehir Ahi Evran Üniversitesi, Türkiye
Alaaddin Coşkun Kirikkale Üniversitesi, Tip Fakültesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Electromagnetic Biology and Medicine (Q3) | ||
| Dergi ISSN | 1536-8378 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 06-2024 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 43 / 3 / 176–186 | DOI | 10.1080/15368378.2024.2366272 |
| Makale Linki | http://dx.doi.org/10.1080/15368378.2024.2366272 | ||
| Özet |
| The size of the pores created by external electrical pulses is important for molecule delivery into the cell. The size of pores and their distribution on the cell membrane determine the efficiency of molecule transport into the cell. There are very few studies visualizing the presence of electropores. In this study, we aimed to investigate the size distribution of electropores that were created by high intensity and short duration electrical pulses on MCF-7 cell membrane. Scanning Electron Microscopy (SEM) was used to visualize and characterize the membrane pores created by the external electric field. Structural changes on the surface of the electroporated cell membrane was observed by Atomic Force Microscopy (AFM). The size distribution of pore sizes was obtained by measuring the radius of 500 electropores. SEM imaging showed non-uniform patterning. The average radius of the electropores was 12 nm, 51.60% of … |
| Anahtar Kelimeler |
| atomic force microscopy | electropermeabilization | Electroporation | human breast cancer cell | pore formation | scanning electron microscopy |
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| Atıf Sayıları | |
| Google Scholar | 2 |
| Scopus | 1 |
| Web of Science | 1 |