| Yazarlar (4) |
Doç. Dr. Özlem GÜNDOĞDU AYTAÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Dr. Öğr. Üyesi Sertan AYTAÇ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Ertan Şahin
Atatürk Üniversitesi, Türkiye |
|
Yunus Kara
Atatürk Üniversitesi, Türkiye |
| Özet |
| The synthesis of new bicyclic lactone derivatives was carried out starting from 2-methyl/phenyl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione. 6-(Hydroxymethyl)-N-methyl/phenylcyclohex-3-ene-1-carboxamide derivatives were obtained from the reduction of tetrahydro-1H-isoindole-1,3(2H)-diones with NaBH4. Bromination and epoxidation reactions of both compounds were examined, and the structures of the resulting products were determined by spectroscopic methods. Substituted bicyclic lactone compounds, which are interesting rearrangement products in both bromination and epoxidation reactions, were obtained. In particular, hydroxymethyl (−CH2OH) and amide (−CONHR) groups attached to the cyclohexene ring in the bromination and epoxidation reactions were found to be effective in product formation. As a result, a new and applicable method was developed for the synthesis of bicyclic lactone … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | ACS Omega |
| Dergi ISSN | 2470-1343 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q2 |
| Makale Dili | Türkçe |
| Basım Tarihi | 05-2024 |
| Cilt No | 9 |
| Sayı | 21 |
| Doi Numarası | 10.1021/acsomega.4c02183 |
| Makale Linki | http://dx.doi.org/10.1021/acsomega.4c02183 |
| Atıf Sayıları |
