| Yazarlar (5) |
Berrak Şekeryapan
Recep Tayyip Erdoğan Üniversitesi, Türkiye |
|
Veysi Öner
Recep Tayyip Erdoğan Üniversitesi, Türkiye |
Prof. Dr. Aynur KIRBAŞ
Recep Tayyip Erdoğan Üniversitesi, Türkiye |
|
Kemal Türkyılmaz
Recep Tayyip Erdoğan Üniversitesi, Türkiye |
|
Mustafa Durmuş
Hitit Üniversitesi, Türkiye |
| Özet |
| Purpose: To compare plasma homocysteine levels between patients with dry eye disease and normal control subjects. Methods: Plasma homocysteine (enzyme immunoassay), vitamin B12, and folate levels were determined in 38 patients with dry eye and in 38 controls. Results: Characteristics of the dry eye and control groups were similar. The mean plasma homocysteine level was 16.38 +/- 6.98 mmol/L in the dry eye group and 14.39 +/- 5.11 mu mol/L in the control group (P = 0.10, t test). Hyperhomocysteinemia was present in the 43.9% of the dry eye patients and 33.3% of the controls (P = 0.43, chi(2) test). There were no statistical differences between dry eye and control groups regarding plasma vitamin B12 and folate levels (P = 0.72 and P = 0.69, respectively, t test). Conclusions: Plasma homocysteine levels in dry eye patients may be inadequate to give homocysteine a role in pathogenesis. However, in ocular diseases like glaucoma, plasma homocysteine levels are significantly higher, and associated dry eye disease may cause an additional increase in plasma homocysteine levels. |
| Anahtar Kelimeler |
| dry eye disease | homocysteine | vitamin B12 | folate |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | CORNEA |
| Dergi ISSN | 0277-3740 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2013 |
| Cilt No | 32 |
| Sayı | 5 |
| Doi Numarası | 10.1097/ICO.0b013e31826f326b |
| Makale Linki | http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00003226-201305000-00025 |
| Atıf Sayıları | |
| WoS | 2 |
| Google Scholar | 5 |
