Plasma Homocysteine Levels in Dry Eye Patients
Yazarlar (5)
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Prof. Dr. Aynur KIRBAŞ
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Hitit Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Cornea |
| Dergi ISSN | 0277-3740 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 05-2013 |
| Cilt No | 32 |
| Sayı | 5 |
| DOI Numarası | 10.1097/ICO.0b013e31826f326b |
| Makale Linki | http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00003226-201305000-00025 |
| Özet |
| Purpose: To compare plasma homocysteine levels between patients with dry eye disease and normal control subjects. Methods: Plasma homocysteine (enzyme immunoassay), vitamin B12, and folate levels were determined in 38 patients with dry eye and in 38 controls. Results: Characteristics of the dry eye and control groups were similar. The mean plasma homocysteine level was 16.38 +/- 6.98 mmol/L in the dry eye group and 14.39 +/- 5.11 mu mol/L in the control group (P = 0.10, t test). Hyperhomocysteinemia was present in the 43.9% of the dry eye patients and 33.3% of the controls (P = 0.43, chi(2) test). There were no statistical differences between dry eye and control groups regarding plasma vitamin B12 and folate levels (P = 0.72 and P = 0.69, respectively, t test). Conclusions: Plasma homocysteine levels in dry eye patients may be inadequate to give homocysteine a role in pathogenesis. However, in ocular diseases like glaucoma, plasma homocysteine levels are significantly higher, and associated dry eye disease may cause an additional increase in plasma homocysteine levels. |
| Anahtar Kelimeler |
| dry eye disease | homocysteine | vitamin B12 | folate |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 2 |
| SCOPUS | 2 |
| Google Scholar | 6 |