Yazarlar |
Semiha Celik Ekinci
|
Ercan Yenilmez
|
Gulfem Akengin Ocal
|
Meliha Cagla Sonmezer
|
Arzu Tarakci
|
Cemanur Aygun
|
Damla Akdag
|
Derya Seyman
|
Cansu Asik
|
Esra Zerdali
|
Fatma Yilmaz Karadag
|
Safak Kaya
|
Mehmet Celik
|
Seyma Cifci
|
Ilknur Esen Yildiz
|
Fatma Colkesen
|
Fethiye Akgul
|
Ozlem Aldemir
|
Merve Bozdag
|
Deniz Ozer
|
Dr. Öğr. Üyesi Lokman HİZMALİ
Kırşehir Ahi Evran Üniversitesi |
Esra Canbolat Unlu
|
Deniz Gur Altunay
|
Ahmet Sahin
|
Gulten Unlue
|
Ayse Eda Gencalioglu
|
Sema Tekin Sahin
|
Yeliz Ozdemir
|
Sibel Unlu
|
Sarp Singil
|
Jale Altintas
|
Sinem Akkaya Isik
|
Ozlem Gul
|
Nazan Tuna
|
Suemeyra Simsek
|
Muge Ozguler
|
Pinar Elbir Kilic
|
Mehmet Emirhan Isik
|
Ayse Karakus
|
Kazim Kiratli
|
Ahmet Cem Yardimci
|
Serkan Volkan
|
Yildiz Olcar
|
Yasemin Cakir
|
Nermin Ozer Yilmaz
|
Serhat Karaayvaz
|
Ayse Batirel
|
Zeynep Cansu Duran
|
Huseyin Kemal Rasa
|
Sukran Kose
|
Özet |
Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP. |
Anahtar Kelimeler |
antibiotic resistance | antimicrobial stewardship | compliance rate of SAP | peri-operative care | surgical antimicrobial prophylaxis |
Makale Türü | Özgün Makale |
Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
Dergi Adı | SURGICAL INFECTIONS |
Dergi ISSN | 1096-2964 |
Dergi Grubu | Q3 |
Makale Dili | İngilizce |
Basım Tarihi | 04-2024 |
Cilt No | 25 |
Sayı | 3 |
Sayfalar | 231 / 239 |
Doi Numarası | 10.1089/sur.2023.243 |