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Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients  
Yazarlar
Semiha Celik Ekinci
Ercan Yenilmez
Gulfem Akengin Ocal
Meliha Cagla Sonmezer
Arzu Tarakci
Cemanur Aygun
Damla Akdag
Derya Seyman
Cansu Asik
Esra Zerdali
Fatma Yilmaz Karadag
Safak Kaya
Mehmet Celik
Seyma Cifci
Ilknur Esen Yildiz
Fatma Colkesen
Fethiye Akgul
Ozlem Aldemir
Merve Bozdag
Deniz Ozer
Dr. Öğr. Üyesi Lokman HİZMALİ Dr. Öğr. Üyesi Lokman HİZMALİ
Kırşehir Ahi Evran Üniversitesi
Esra Canbolat Unlu
Deniz Gur Altunay
Ahmet Sahin
Gulten Unlue
Ayse Eda Gencalioglu
Sema Tekin Sahin
Yeliz Ozdemir
Sibel Unlu
Sarp Singil
Jale Altintas
Sinem Akkaya Isik
Ozlem Gul
Nazan Tuna
Suemeyra Simsek
Muge Ozguler
Pinar Elbir Kilic
Mehmet Emirhan Isik
Ayse Karakus
Kazim Kiratli
Ahmet Cem Yardimci
Serkan Volkan
Yildiz Olcar
Yasemin Cakir
Nermin Ozer Yilmaz
Serhat Karaayvaz
Ayse Batirel
Zeynep Cansu Duran
Huseyin Kemal Rasa
Sukran Kose
Özet
Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP.
Anahtar Kelimeler
antibiotic resistance | antimicrobial stewardship | compliance rate of SAP | peri-operative care | surgical antimicrobial prophylaxis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı SURGICAL INFECTIONS
Dergi ISSN 1096-2964
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 04-2024
Cilt No 25
Sayı 3
Sayfalar 231 / 239
Doi Numarası 10.1089/sur.2023.243