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Surgical Antimicrobial Prophylaxis Compliance in Turkey: Data from the Prospective, Observational, Multicenter Survey Including 7,978 Surgical Patients   
Yazarlar (50)
Semiha Celik Ekinci
University of Health Sciences Turkey, Türkiye
Ercan Yenilmez
University of Health Sciences Turkey, Türkiye
Gulfem Akengin Ocal
University of Health Sciences Turkey, Türkiye
Meliha Cagla Sonmezer
Hacettepe University, Türkiye
Arzu Tarakci
Konya City Hospital, Türkiye
Cemanur Aygun
University of Health Sciences Turkey, Türkiye
Damla Akdag
Basaksehir Cam & Sakura City Hosp, Türkiye
Derya Seyman
Antalya Training & Research Hospital, Türkiye
Cansu Asik
Istanbul Haydarpasa Numune Training & Research Hospital, Türkiye
Esra Zerdali
University of Health Sciences Turkey, Türkiye
Fatma Yilmaz Karadag
University of Health Sciences Turkey, Türkiye
Safak Kaya
Diyarbakir Training & Research Hospital, Türkiye
Mehmet Celik
Harran University, Türkiye
Seyma Cifci
Nevsehir State Hospital, Türkiye
Ilknur Esen Yildiz
Recep Tayyip Erdogan University, Türkiye
Fatma Colkesen
Konya Numune Hospital, Türkiye
Fethiye Akgul
Batman Training & Res Hosp, Türkiye
Ozlem Aldemir
Sivas Numune Hospital, Türkiye
Merve Bozdag
Gulhane Training & Research Hospital, Türkiye
Deniz Ozer
Celal Bayar University, Türkiye
Dr. Öğr. Üyesi Lokman HİZMALİ Dr. Öğr. Üyesi Lokman HİZMALİ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Esra Canbolat Unlu
Bakirkoy Dr. Sadi Konuk Research & Training Hospital, Türkiye
Deniz Gur Altunay
University of Health Sciences Turkey, Türkiye
Ahmet Sahin
Dr. Ersin Arslan Education & Research Hospital, Türkiye
Gulten Unlue
Kocaeli Derince Training & Research Hospital, Türkiye
Ayse Eda Gencalioglu
Fatih State Hospital, Türkiye
Sema Tekin Sahin
Alanya Training & Res Hosp, Türkiye
Yeliz Ozdemir
Izmir Bozyaka Training & Research Hospital, Türkiye
Sibel Unlu
Mersin Toros State Hospital, Türkiye
Sarp Singil
University of Health Sciences Turkey, Türkiye
Jale Altintas
Gebze Fatih State Hospital, Türkiye
Sinem Akkaya Isik
University of Health Sciences Turkey, Türkiye
Ozlem Gul
University of Health Sciences Turkey, Türkiye
Nazan Tuna
Namik Kemal University, Türkiye
Suemeyra Simsek
Tekirdag Corlu State Hospital, Türkiye
Muge Ozguler
University of Health Sciences Turkey, Türkiye
Pinar Elbir Kilic
Tuzla State Hospital, Türkiye
Mehmet Emirhan Isik
University of Health Sciences Turkey, Türkiye
Ayse Karakus
Hendek State Hospital, Türkiye
Kazim Kiratli
Izmir Ataturk Training & Research Hospital, Türkiye
Ahmet Cem Yardimci
VM Med Pk Mersin Hosp, Türkiye
Serkan Volkan
Aydin State Hospital, Türkiye
Yildiz Olcar
Kastamonu Training & Res Hosp, Türkiye
Yasemin Cakir
Cumhuriyet University, Türkiye
Nermin Ozer Yilmaz
University of Health Sciences Turkey, Türkiye
Serhat Karaayvaz
Ezine State Hospital, Türkiye
Ayse Batirel
University of Health Sciences Turkey, Türkiye
Zeynep Cansu Duran
Hacettepe University, Türkiye
Huseyin Kemal Rasa
Anadolu Med Ctr Gebze, Türkiye
Sukran Kose
Dokuz Eylul University, Türkiye
Devamını Göster
Özet
Background: Surgical antimicrobial prophylaxis (SAP) is the peri-operative administration of antimicrobial agents. Compliance rates vary worldwide from 15% to 84.3%, with studies in Turkey not exceeding 35%. The aim of this multicenter study was to determine the rate of appropriate antibiotic class, timing, and duration as well as discharge prescriptions in Turkey. Thus, we aimed to determine the rate of full compliance with SAP procedures in our country Patients and Methods: This multicenter, prospective, observational, descriptive study was conducted in 47 hospitals from 28 provinces in seven different regions of Turkey. Patients over 18 years of age in all surgical units between June 6, 2022, and June 10, 2022, were included in the study. Results: Of the 7,978 patients included in the study, 332 were excluded from further analyses because of pre-existing infection, and SAP compliance analyses were performed on the remaining 7,646 cases. The antibiotic most commonly used for SAP was cefazolin (n = 4,701; 61.5%), followed by third-generation cephalosporins (n = 596; 7.8%). The most common time to start SAP was within 30 minutes before surgery (n = 2,252; 32.5%), followed by 30 to 60 minutes before surgery (n = 1,638; 23.6%). Surgical antimicrobial prophylaxis duration was <24 hours in 3,516 (50.7%) patients and prolonged until discharge in 1,505 (21.7%) patients. Finally, the actual proportion of patients compliant with SAP was 19% (n = 1,452) after omitting 4,458 (58.3%) patients who were prescribed oral antibiotic agents at discharge as part of a prolonged SAP. Conclusions: Surgical antimicrobial prophylaxis compliance rates are still very low in Turkey. Prolonged duration of SAP and especially high rate of antibiotic prescription at discharge are the main reasons for non-compliance with SAP.
Anahtar Kelimeler
antibiotic resistance | antimicrobial stewardship | compliance rate of SAP | peri-operative care | surgical antimicrobial prophylaxis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı SURGICAL INFECTIONS
Dergi ISSN 1096-2964 Wos Dergi Scopus Dergi
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 04-2024
Cilt No 25
Sayı 3
Sayfalar 231 / 239
DOI Numarası 10.1089/sur.2023.243