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Evaluation of the effects of fasting associated dehydration on maternal NGAL levels and fetal renal artery Doppler parameters      
Yazarlar
Yeşim Bayoğlu Tekin
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Emine Seda Güvendağ Güven
Karadeniz Teknik Üniversitesi, Türkiye
Ülkü Mete Ural
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Zihni Açar Yazıcı
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Prof. Dr. Aynur KIRBAŞ
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Figen Kır Şahin
Recep Tayyip Erdoğan Üniversitesi, Türkiye
Özet
Objective: The aim of this study was to evaluate maternal neutrophil gelatinase-asssociated lipocalin (NGAL) levels and fetal renal artery (fRA) Doppler flow indices in pregnant women fasting in Ramadan in respect of dehydration in long hot summer days as a marker of hypoperfusion and early renal injury.Methods: A cross-sectional observational study was carried out at a University Hospital. Fasting pregnant women and non-fasting age, gravidity and gestational age-matched women were evaluated for hematologic, blood biochemistry and urine parameters in the first and fourth weeks of the Ramadan. Umbilical artery and fRA Doppler flows were studied in each evaluation.Results: Blood urea nitrogen, potassium and hematocrit levels, blood and urine NGAL levels were significantly higher, and fRA Doppler indices increased in fasting women (p<0.05) during the second visit in the last week of the Ramadan, while non-fasting women had no significant alterations in each evaluation (p>0.05).Conclusions: Adequate maternal vascular volume is essential for the maintenance of healthy pregnancy. Fasting during the long and hot summer days leads to fluid deprivation and dehydration which was found to be related to subclinical maternal renal dysfunction and increased fRA Doppler indices.
Anahtar Kelimeler
Fetal renal artery Doppler, maternal dehydration, NGAL, pregnancy, Ramadan fasting, renal function
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı The Journal of Maternal-Fetal & Neonatal Medicine
Dergi ISSN 1476-7058
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 02-2016
Cilt No 29
Sayı 4
Sayfalar 629 / 632
Doi Numarası 10.3109/14767058.2015.1014789
Makale Linki http://www.tandfonline.com/doi/full/10.3109/14767058.2015.1014789