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Synthesis of chiral diaza 18-crown-6 ethers from chiral amines and molecular recognition of potassium and sodium salts of amino acids  
Yazarlar
N. Demirel
Dicle Üniversitesi, Turkey
Y. Bulut
Dicle Üniversitesi, Turkey
Özet
A practical synthesis of chiral amine precursors 3 and 4 and chiral diaza 18-crown-6 ethers 5, 6 and 7 starting from chiral amines are reported. The molecular recognition of these chiral crown ethers for amino acids potassium and sodium salts has been characterized by UV-vis. The selectivity order is Phe>Thr>Ala. In the case of 6 the cavity of the macrocycle plays an important role in recognition. © 2003 Elsevier Ltd. All rights reserved.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SCOPUS dergilerinde yayımlanan tam makale
Dergi Adı Tetrahedron Asymmetry
Dergi ISSN 0957-4166
Makale Dili İngilizce
Basım Tarihi 09-2003
Cilt No 14
Sayı 17
Sayfalar 2633 / 2637
Doi Numarası 10.1016/S0957-4166(03)00594-9