Yazarlar |
Dr. Öğr. Üyesi Ertan KATIRCI
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Remziye Kendirci-Katirci
|
Emin Türkay Korgun
Akdeniz Üniversitesi, Türkiye |
Özet |
Innate lymphoid cells (ILCs) are involved in the innate immune system because they lack specific antigen receptors and lineage markers. ILCs also display phenotypic and characteristic features of adaptive immune cells. Therefore, ILCs are functional in essential interactions between adaptive and innate immunity. ILCs are found in both lymphoid and nonlymphoid tissues and migrate to the area of inflammation during the inflammatory process. ILCs respond to pathogens by producing a variety of cytokines and are involved in the barrier defense of antigens and in many immunological processes such as allergic events. Recent research has shown that ILCs are functional during human pregnancy and have been suggested to be essential for the healthy progression of pregnancy. In this review, we focus on the role of ILCs in human pregnancy by discussing the relationship between ILCs and the pregnancy microenvironment, specifically summarizing the role of ILCs in physiological and pathological pregnancies. |
Anahtar Kelimeler |
adaptive immunity | cytokines | innate immunity | innate lymphoid cells | pregnancy | transcription factors |
Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
Dergi Adı | AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY |
Dergi ISSN | 1046-7408 |
Dergi Tarandığı Indeksler | SCI-Expanded |
Makale Dili | İngilizce |
Basım Tarihi | 03-2024 |
Cilt No | 91 |
Sayı | 3 |
Doi Numarası | 10.1111/aji.13834 |
Makale Linki | http://dx.doi.org/10.1111/aji.13834 |