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Are innate lymphoid cells friend or foe in human pregnancy?     
Yazarlar
Dr. Öğr. Üyesi Ertan KATIRCI Dr. Öğr. Üyesi Ertan KATIRCI
Kırşehir Ahi Evran Üniversitesi, Türkiye
Remziye Kendirci-Katirci
Emin Türkay Korgun
Akdeniz Üniversitesi, Türkiye
Özet
Innate lymphoid cells (ILCs) are involved in the innate immune system because they lack specific antigen receptors and lineage markers. ILCs also display phenotypic and characteristic features of adaptive immune cells. Therefore, ILCs are functional in essential interactions between adaptive and innate immunity. ILCs are found in both lymphoid and nonlymphoid tissues and migrate to the area of inflammation during the inflammatory process. ILCs respond to pathogens by producing a variety of cytokines and are involved in the barrier defense of antigens and in many immunological processes such as allergic events. Recent research has shown that ILCs are functional during human pregnancy and have been suggested to be essential for the healthy progression of pregnancy. In this review, we focus on the role of ILCs in human pregnancy by discussing the relationship between ILCs and the pregnancy microenvironment, specifically summarizing the role of ILCs in physiological and pathological pregnancies.
Anahtar Kelimeler
adaptive immunity | cytokines | innate immunity | innate lymphoid cells | pregnancy | transcription factors
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü SCI, SSCI, AHCI, SCI-Exp dergilerinde yayımlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale
Dergi Adı AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Dergi ISSN 1046-7408
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 03-2024
Cilt No 91
Sayı 3
Doi Numarası 10.1111/aji.13834
Makale Linki http://dx.doi.org/10.1111/aji.13834
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Are innate lymphoid cells friend or foe in human pregnancy?

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