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Effects of sugammadex on platelet levels and platelet-to-lymphocyte ratio in morbidly obese patients undergoing sleeve gastrectomy   
Yazarlar
Prof. Dr. Özkan GÖRGÜLÜ Prof. Dr. Özkan GÖRGÜLÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Özet
Sugammadex is known to have minimal effects on coagulopathy. The aim of this study was to analyse the changes in platelet levels and platelet-to-lymphocyte ratio (PLR) in preoperative and postoperative periods in morbidly obese patients. This retrospective study included a total of 86 morbidly obese patients with a Body Mass Index (BMI) of> 40 kg/m2 and with an American Society of Anaesthesiologists Classification score (ASA) III undergoing elective laparoscopic sleeve gastrectomy (LSG). Patient data were obtained from patient files and electronic health records system (SARUS). The patients were allocated into two groups namely sugammadex (Group S) and neostigmine (Group N). Preoperative and postoperative (12th hour) hemogram recordings of the patients were examined. Compared to preoperative levels, there was a significant decrease in the postoperative platelet and lymphocyte values of patients in Group S (p< 0.001) whereas postoperative PLR values were significantly increased (p< 0.001). The comparison of the preoperative and postoperative values of patients in Group S according to gender showed no significant difference (p> 0.05). Although sugammadex causes a decrease in the platelet and lymphocyte levels in the postoperative period similar to neostigmine, a relatively higher decrease in lymphocyte levels caused an increase in PLR values. None of the morbidly obese patients, who were administrated sugammadexn (2 mg kg-1) via intravenous administration, underwent reoperation in the postoperative period due to coagulopathy.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Medicine
Dergi Tarandığı Indeksler
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 01-2021
Cilt No 10
Sayı 1
Sayfalar 106 / 10
BM Sürdürülebilir Kalkınma Amaçları
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