| Yazarlar |
Zeliha Hayvali
|
|
Huseyin Guler
|
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi |
|
Nursen Sari
|
| Özet |
| A series of new compounds containing formyl and imine group were synthesized. New formyl-substituted compounds were prepared by the reaction of 1,2-bis(bromomethyl)benzene with benzaldehyde derivatives in the presence of NaOH. New bis-crown ether imine compounds were prepared by the condensation of corresponding aldehydes with 4'-aminobenzo-15-crown-5. Sodium complexes of the bis-crown ethers form crystalline 2:1 (Na+:ligand) stoichiometries were also been synthesized. The prepared compounds were structurally confirmed by analytical and spectral data and evaluated for their antibacterial and antifungal activities. The results show that the antibacterial activity of compounds including o-methoxy group was significantly higher against S. epidermis compared to the other studied antimicrobial group. |
| Anahtar Kelimeler |
| bis-Crown ethers | Schiff bases | Aldehydes | Antibacterial activity | Sodium complexes |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | MEDICINAL CHEMISTRY RESEARCH |
| Dergi ISSN | 1054-2523 |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2014 |
| Cilt No | 23 |
| Sayı | 8 |
| Sayfalar | 3652 / 3661 |
| Doi Numarası | 10.1007/s00044-014-0937-9 |
| Atıf Sayıları | |
| WoS | 16 |
