Alleviation of Aluminum-Induced Oxidative Stress, Trace Element, and Mineral Levels in Rat Tissues Protective Role of Pomegranate Juice (Punica Granatum L.)
 
Yazarlar (6)
Prof. Dr. Harun ÇİFTÇİ Kırşehir Ahi Evran Üniversitesi, Türkiye
Doç. Dr. Çiğdem ER ÇALIŞKAN Kırşehir Ahi Evran Üniversitesi, Türkiye
Habibe Koç
Kırşehir Ahi Evran Üniversitesi, Türkiye
Dr. Öğr. Üyesi Kübra ÖZTÜRK Kırşehir Ahi Evran Üniversitesi, Türkiye
Ahmet Özkaya Adiyaman Üniversitesi, Türkiye
Doç. Dr. Zeynel Abidin ERBESLER Kırşehir Ahi Evran Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Biological Trace Element Research (Q2)
Dergi ISSN 0163-4984 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 12-2023
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 202 / 9 / 4146–4157 DOI 10.1007/s12011-023-03997-2
Makale Linki http://dx.doi.org/10.1007/s12011-023-03997-2
Özet
The present investigation examined the impact of pomegranate (Punica granatum L.) juice on trace elements, minerals, and oxidative stress in relation to the potential harm inflicted by aluminum chloride (AlCl3) in rats. Rats were split into four groups at random for this purpose: control (C), pomegranate juice (PJ), aluminum chloride (A), and PJ + A. For 30 days, PJ was orally administered by gavage at a rate of 4 mL/kg every other day, whereas AlCl3 was administered intraperitoneally at 8.3 mg/kg. Spectrophotometric analysis was used to measure the levels of malondialdehyde (MDA), glutathione (GSH), superoxide dismutase (SOD), and catalase (CAT) enzyme activity in various tissues. In addition, high-resolution continuum source flame atomic absorption spectrometry (HR-CS FAAS) was used to determine the amounts of the elements Al, Cu, Fe, Mn, Zn, Ca, and Mg in the tissues. It was discovered that when …
Anahtar Kelimeler
Aluminum | Antioxidant | Brain | Kidney | Liver | Pomegranate (Punica granatum L.) juice | Trace element