Copper(II) sulfonamide complexes having enzyme inhibition activities on carbonic anhydrase I: synthesis, characterization and inhibition studies
Yazarlar (6)
Demet Uzun Gazi Üniversitesi, Türkiye
Ayla Balaban Gündüzalp Gazi Üniversitesi, Türkiye
Gökhan Parlakgümüş
Gazi Üniversitesi, Türkiye
Gazi Üniversitesi, Türkiye
Ümmühan Özdemir Özmen Gazi Üniversitesi, Türkiye
Prof. Dr. Neslihan ÖZBEK Kırşehir Ahi Evran Üniversitesi, Türkiye
Ebru Aktan Gazi Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of the Iranian Chemical Society | ||
| Dergi ISSN | 1735-207X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2022 |
| Cilt / Sayı / Sayfa | 19 / 1 / 55–69 | DOI | 10.1007/s13738-021-02287-9 |
| Özet |
| In our present study, copper(II) sulfonamide complexes titled as bis-(2 acetylfuranmethanesulfonylhydrazone) copper(II) chloride, bis-(2-furaldehydemethanesulfonylhydrazone)copper(II) chloride and bis-(5-nitro-2 furaldehydemethanesulfonylhydrazone)copper(II) chloride were synthesized using aromatic sulfonylhydrazones derived from methane sulfonic acid hydrazide. The structures of copper(II) sulfonamides were determined by using LC–MS, FT-IR and UV–Vis methods, magnetism and conductivity measurements, and also electrochemical studies. In order to gain insight into the structure of the copper(II) complexes, computational studies were performed by using DFT/B3LYP/6-311G(d,p) basis set with the Gaussian 09 program package. In general, sulfonamides and their derivatives are researched for their inhibitory effects on carbonic anhydrase isoenzymes (CAs). Synthesized copper(II) complexes have … |
| Anahtar Kelimeler |
| Carbonic anhydrase I | Enzyme inhibition | Sulfonamide | Voltammetry |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 3 |
| SCOPUS | 3 |
| Google Scholar | 3 |