| Yazarlar (7) |
HATİCE FULYA AKIN
|
|
SEBAHAT TURGUT
|
|
MEHMET BAŞTEMİR
|
|
GÜNFER TURGUT
|
|
RAZİYE AKCILAR
|
|
UĞUR KARASU
|
Prof. Dr. Aydın GÜÇLÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| The aim of this study was to analyze the distribution of the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene in obese Turkish patients with insulin resistance (IR). Sixty-two obese Turkish patients with IR were enrolled in this study. One hundred healthy people without IR were recruited as the control group. ACE amplification was performed by polymerase chain reaction. The frequency of the DD genotype was significantly higher in obese patients with IR than in control subjects. Of sixty-two patients, 1 (1.6%) had an II genotype, 22 (35.5%) had an ID genotype, and 39 (62.9%) had a DD genotype. The frequency of the I allele in the patient group was significantly lower than in controls. We found that the frequency of the DD genotype was higher in obese Turkish patients with IR. ACE gene I/D polymorphism may be associated with obesity in the Turkish population. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | DNA and Cell Biology |
| Dergi ISSN | 1044-5498 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2010 |
| Cilt No | 29 |
| Sayı | 4 |
| Sayfalar | 207 / 212 |
| Doi Numarası | 10.1089/dna.2009.0934 |
| Makale Linki | http://www.liebertonline.com/doi/abs/10.1089/dna.2009.0934 |
| Atıf Sayıları | |
| WoS | 16 |
