Yazarlar |
Özge Çağlar Tekinel
|
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
Doğukan Doyduk
Türkiye |
Ali Dişli
Türkiye |
Özet |
In this study, a synthetic route to access unsymmetrical ditetrazoles was developed. By using this method, the first examples of unsymmetrical thioditetrazole compounds were synthesized. In vitro, antibacterial efficacy studies were carried out for all the thioditetrazoles and their precursor thiotetrazoles against ten bacteria. The synthesized compounds showed a strong antibacterial effect against pathogenic Gram-negative bacteria, especially Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa (up to 23 mm). |
Anahtar Kelimeler |
Tetrazole | thiotetrazole | dithiotetrazole | antibacterial activity | antifungal activity |
Makale Türü | Özgün Makale |
Makale Alt Türü | ESCI dergilerinde yayımlanan tam makale |
Dergi Adı | ACG Publications |
Dergi ISSN | 1307-6175 |
Dergi Tarandığı Indeksler | Google Scholar, idealonline, ROAD, SOBIAD, CrossRef, ResearchBib, Rootindexing |
Makale Dili | Türkçe |
Basım Tarihi | 10-2023 |
Cilt No | 16 |
Sayı | 4 |
Sayfalar | 204 / 211 |
Doi Numarası | 10.25135/acg.oc.158.2309.2893 |
Makale Linki | http://dx.doi.org/10.25135/acg.oc.158.2309.2893 |