Synthesis and antimicrobial activities of unsymmetrical thioditetrazoles and their precursor thiotetrazoles
Yazarlar (4)
Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Gazi University, Türkiye
Gazi University, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
|
||
| Dergi Adı | ORGANIC COMMUNICATIONS | ||
| Dergi ISSN | 1307-6175 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | Google Scholar, idealonline, ROAD, SOBIAD, CrossRef, ResearchBib, Rootindexing | ||
| Makale Dili | Türkçe | Basım Tarihi | 10-2023 |
| Cilt / Sayı / Sayfa | 16 / 4 / 204–211 | DOI | 10.25135/acg.oc.158.2309.2893 |
| Makale Linki | http://dx.doi.org/10.25135/acg.oc.158.2309.2893 | ||
| Özet |
| In this study, a synthetic route to access unsymmetrical ditetrazoles was developed. By using this method, the first examples of unsymmetrical thioditetrazole compounds were synthesized. In vitro, antibacterial efficacy studies were carried out for all the thioditetrazoles and their precursor thiotetrazoles against ten bacteria. The synthesized compounds showed a strong antibacterial effect against pathogenic Gram-negative bacteria, especially Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa (up to 23 mm). |
| Anahtar Kelimeler |
| Tetrazole | thiotetrazole | dithiotetrazole | antibacterial activity | antifungal activity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları |