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Synthesis and antimicrobial activities of unsymmetrical thioditetrazoles and their precursor thiotetrazoles    
Yazarlar
Özge Çağlar Tekinel
Prof. Dr. Hatice ÖĞÜTCÜ Prof. Dr. Hatice ÖĞÜTCÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye
Doğukan Doyduk
Türkiye
Ali Dişli
Türkiye
Özet
In this study, a synthetic route to access unsymmetrical ditetrazoles was developed. By using this method, the first examples of unsymmetrical thioditetrazole compounds were synthesized. In vitro, antibacterial efficacy studies were carried out for all the thioditetrazoles and their precursor thiotetrazoles against ten bacteria. The synthesized compounds showed a strong antibacterial effect against pathogenic Gram-negative bacteria, especially Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa (up to 23 mm).
Anahtar Kelimeler
Tetrazole | thiotetrazole | dithiotetrazole | antibacterial activity | antifungal activity
Makale Türü Özgün Makale
Makale Alt Türü ESCI dergilerinde yayımlanan tam makale
Dergi Adı ACG Publications
Dergi ISSN 1307-6175
Dergi Tarandığı Indeksler Google Scholar, idealonline, ROAD, SOBIAD, CrossRef, ResearchBib, Rootindexing
Makale Dili Türkçe
Basım Tarihi 10-2023
Cilt No 16
Sayı 4
Sayfalar 204 / 211
Doi Numarası 10.25135/acg.oc.158.2309.2893
Makale Linki http://dx.doi.org/10.25135/acg.oc.158.2309.2893