Response to a Letter to the Editor Entitled "Low Serum B12 Level Does Not Mean Vit. B12 Deficiency-Problems Related to the Diagnosis of Vitamin B12 Deficiency"      
Yazarlar (6)
Veysi Oner
Recep Tayyip Erdogan University, Türkiye
Kemal Turkylmaz
Recep Tayyip Erdogan University, Türkiye
Aysegul Kucukali Turkyilmaz
Recep Tayyip Erdogan University, Türkiye
Prof. Dr. Aynur KIRBAŞ Recep Tayyip Erdogan University, Türkiye
Serkan Kirbas
Recep Tayyip Erdogan University, Türkiye
Berrak Sekeryapan
Recep Tayyip Erdogan University, Türkiye
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri)
Makale Alt Türü
Dergi Adı Current Eye Research
Dergi ISSN 0271-3683 Wos Dergi Scopus Dergi
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 04-2014
Cilt No 39
Sayı 4
Sayfalar 427 / 428
DOI Numarası 10.3109/02713683.2013.833249
Özet
We thank Dr Grzybowski 1 for the interest he has shown in our article entitled ‘‘Evaluation of peripapillary retinal nerve fiber layer thickness in patients with vitamin B12 deficiency using spectral domain optical coherence tomography’’. 2 Firstly, Dr Grzybowski argues that low serum vitamin B12 level is not automatically diagnostic for vitamin B12 deficiency in asymptomatic, hematologically normal patients. He states that the clinical picture is crucial for determination of the vitamin B12 deficiency. In addition, he says that the levels of the other biomarkers such as methylmalonic acid or homocysteine could be used for the diagnosis. In our study, we used serum vitamin B12 levels, clinico-electrophysiological evaluation and spinal magnetic resonance imaging for the diagnosis of vitamin B12 deficiency and related neuropathies. Eight patients had clinical vitamin B12 deficiency. However, the rest of the patients (37 …
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