Urinary early kidney injury molecules in children with beta-thalassemia major
Yazarlar (10)
Prof. Dr. Velat Sen Dicle University, Faculty Of Medicine, Türkiye
Aydin Ece
Dicle University, Faculty Of Medicine, Türkiye
Dicle University, Faculty Of Medicine, Türkiye
Unal Uluca
Dicle University, Faculty Of Medicine, Türkiye
Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Murat Soker Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Ali GÜNEŞ Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Ibrahim Kaplan Dicle University, Faculty Of Medicine, Türkiye
Ilhan Tan
Dicle University, Faculty Of Medicine, Türkiye
Dicle University, Faculty Of Medicine, Türkiye
Servet Yel Dicle University, Faculty Of Medicine, Türkiye
Prof. Dr. Nuriye Mete Dicle University, Faculty Of Medicine, Türkiye
Arş. Gör. Cahit Sahin Dicle University, Faculty Of Medicine, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Renal Failure (Q4) | ||
| Dergi ISSN | 0886-022X Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 05-2015 |
| Cilt / Sayı / Sayfa | 37 / 4 / 607–613 | DOI | 10.3109/0886022X.2015.1007871 |
| Makale Linki | https://publons.com/wos-op/publon/13319410/ | ||
| UAK Araştırma Alanları |
Sağlık Bilimleri
|
||
| Özet |
| Background: The aim of this study was to investigate novel urinary biomarkers including N-acetyl-β-d-glucosaminidase (NAG), neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and liver-type fatty acid binding protein (L-FABP) in children with β-thalassemia major (β-TM). Materials and methods: Totally, 52 patients (29 boys, 23 girls) with β-TM and 29 healthy controls (3–17 years) were included. Various demographic characteristics and blood transfusions/year, disease duration, and chelation therapy were recorded. Serum urea, creatinine, electrolytes, and ferritin and urinary creatinine, protein, calcium, phosphorus, sodium, potassium, and uric acid in first morning urine samples were measured and estimated glomerular filtration rate (eGFR) was calculated. Routine serum and urinary biochemical variables, urinary NAG to Creatinine (UNAG/Cr), UNGAL/Cr, UKIM-1/Cr, and UL … |
| Anahtar Kelimeler |
| Early molecule | FABP | Kidney injury | KIM-1 | NAG | NGAL | Thalassemia |
