| Yazarlar |
Atilla Icli
|
|
Fatih Aksoy
|
|
Abdullah Dogan
|
|
Akif Arslan
|
|
Ibrahim Ersoy
|
|
Habil Yucel
|
Özkan GÖRGÜLÜ
Kırşehir Ahi Evran Üniversitesi, Türkiye |
| Özet |
| Thromboembolic events can be seen in patients with mitral valve prolapse (MVP). It is unclear whether platelet activation may contribute to these events in patients with MVP. Thus, we aimed to evaluate mean platelet volume (MPV) in patients with MVP and its association with the severity of MVP. This study included 312 patients with MVP and 240 control participants. Mean platelet volume was significantly higher in patients with MVP than in controls (8.9 ± 0.7 vs 7.9 ± 0.6 fL, P =.001). In linear regression analysis, MPV was independently associated with the degree of mitral regurgitation (β =.23, 95% confidence interval (CI): 0.14-0.32, P =.001), maximal leaflet displacement (β =.24, 95%CI: 0.17-0.31, P =.001), and mean thickness of the anterior (β =.47, 95%CI: 0.27-0.61, P =.001) and posterior leaflets (β =.22, 95%CI: 0.03-0.41, P =.02). Our findings show that MPV can be elevated in patients with MVP and may be independently associated with severity of mitral regurgitation, leaflet displacement, and thickness of the leaflets. © 2013 The Author(s). |
| Anahtar Kelimeler |
| mean platelet volume | mitral valve prolapse | platelet activation | thrombus |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SCOPUS dergilerinde yayımlanan tam makale |
| Dergi Adı | CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS |
| Dergi ISSN | 1076-0296 |
| Makale Dili | İngilizce |
| Basım Tarihi | 11-2013 |
| Cilt No | 19 |
| Sayı | 6 |
| Sayfalar | 608 / 612 |
| Doi Numarası | 10.1177/1076029612461847 |
| Atıf Sayıları | |
| WoS | 3 |
| SCOPUS | 3 |
