| Yazarlar (9) |
Murat Salih Güneş
Türkiye |
|
İsmail Külahlı
Akdeniz Üniversitesi, Türkiye |
|
Kerem Kökoğlu
Erciyes Üniversitesi, Türkiye |
|
Alperen Vural
İstanbul Üniversitesi-Cerrahpaşa, Türkiye |
|
Deniz Avcı
Türkiye |
|
Şafak Güleç
İstanbul Medipol Üniversitesi, Türkiye |
|
Mehmet Fatih Sönmez
Türkiye |
Dr. Öğr. Üyesi Kübra Tuğçe KALKAN
Kırşehir Ahi Evran Üniversitesi, Türkiye |
|
Barış Derya Erçal
Türkiye |
| Özet |
| IntroductionAllergic Rhinitis (AR) effects 20–40% of the global population and its prevalance increases. Medical treatment and immunotherapy could be used in AR management. But they are not definitive solution. Medical treatment must be used a long time and has side effects. Immunotherapy cannot be applied to every patient and it also takes a long time. The aim of this study is to evaluate symptomatic and histopathological effects of intranasal infiltrated Botulinum Toxin-A (Btx-A) on an animal model of AR.Material-Method15 rabbits were divided into 3 groups as control, disease and treatment. AR was formed in disease and treatment groups by intraperitoneal and intranasal ovalbumine. Allergic symptoms were observed and serum IgE levels were estimated to prove forming of AR. Btx-A was infiltrated in inferior turbinates of rabbits in treatment group. Rabbits were sacrified on 32nd day. Paranasal structures … |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | International journal of pediatric otorhinolaryngology |
| Dergi ISSN | 0165-5876 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-2016 |
| Cilt No | 83 |
| Sayfalar | 51 / 56 |
| Doi Numarası | 10.1016/j.ijporl.2016.01.010 |
| Makale Linki | http://dx.doi.org/10.1016/j.ijporl.2016.01.010 |
| Atıf Sayıları | |
| Google Scholar | 10 |
