Retrobulbar Neuritis as the Initial Sign of Interferon-Alpha-Associated Multiple Sclerosis in a Chronic Hepatitis B Patient: Case Report
Yazarlar (4)
Prof. Dr. Kemal ÖRNEK Kirikkale Üniversitesi, Türkiye
Zafer Onaran Kirikkale Üniversitesi, Türkiye
Pelin Yilmazbas
Kirikkale Üniversitesi, Türkiye
Sefa Guliter
Kirikkale Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Turkiye Klinikleri Journal of Medical Sciences (Q4)
Dergi ISSN 1300-0292 Wos Dergi Scopus Dergi
Makale Dili İngilizce Basım Tarihi 06-2011
Kabul Tarihi 12-04-2026 Yayınlanma Tarihi
Cilt / Sayı / Sayfa 31 / 3 / 716–719 DOI 10.5336/medsci.2009-13361
Makale Linki https://pdfs.semanticscholar.org/9509/a035eaf8fff11c60d59796258fa9d431ea82.pdf
Özet
ABS TRACT Interferon-alpha (IFN-α) is a therapeutic agent which plays an important role in the management of viral and malignant disorders. However, it has several side effects on eye and visual pathway. A 43-year-old man was admitted with sudden loss of vision. He had been on IFN-α treatment for chronic hepatitis B which was stopped 9 months earlier. The diagnosis of retrobulbar optic neuritis was made. Six months later, he admitted to us with decreased vision in the same eye. Magnetic resonance imaging of the brain revealed white matter lesions. Further neurological investigations confirmed the diagnosis of multiple sclerosis. Multiple sclerosis should be considered in differential diagnosis of hepatitis B patients with a history of IFN-α treatment who present with visual symptoms.
Anahtar Kelimeler
Chronic | Hepatitis B | Interferon-alpha | Multiple sclerosis | Optic neuritis