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Retrobulbar Neuritis as the Initial Sign of Interferon-Alpha-Associated Multiple Sclerosis in a Chronic Hepatitis B Patient: Case Report  
Yazarlar
Prof. Dr. Kemal ÖRNEK
Kırşehir Ahi Evran Üniversitesi
Zafer Onaran
Pelin Yilmazbas
Sefa Guliter
Özet
Interferon-alpha (IFN-alpha) is a therapeutic agent which plays an important role in the management of viral and malignant disorders. However, it has several side effects on eye and visual pathway. A 43-year-old man was admitted with sudden loss of vision. He had been on IFN-alpha treatment for chronic hepatitis B which was stopped 9 months earlier. The diagnosis of retrobulbar optic neuritis was made. Six months later, he admitted to us with decreased vision in the same eye. Magnetic resonance imaging of the brain revealed white matter lesions. Further neurological investigations confirmed the diagnosis of multiple sclerosis. Multiple sclerosis should be considered in differential diagnosis of hepatitis B patients with a history of IFN-alpha treatment who present with visual symptoms.
Anahtar Kelimeler
Hepatitis B, chronic, interferon-alpha, multiple sclerosis, optic neuritis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
Dergi ISSN 1300-0292
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 60-2011
Cilt No 31
Sayı 3
Sayfalar 716 / 719
Doi Numarası 10.5336/medsci.2009-13361