Clinical and Demographic Features of Children Diagnosed with Cystic Fibrosis after Sweat Test Screening for Failure to Thrive, Chronic Diarrhea or Recurrent Pulmonary Infections
Yazarlar (7)
Capan Konca Adiyaman Üniversitesi, Türkiye
Prof. Dr. Ali GÜNEŞ Dicle Üniversitesi, Türkiye
Velat Sen Dicle Üniversitesi, Türkiye
Servet Yel Dicle Üniversitesi, Türkiye
Ilyas Yolbas Dicle Üniversitesi, Türkiye
Aydin Ece Dicle Üniversitesi, Türkiye
Mehmet Fuat Gurkan Dicle Üniversitesi, Türkiye
Makale Türü Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Guncel Pediatri
Dergi ISSN 1304-9054 Dergi Bilgileri (2013)
Makale Dili İngilizce Basım Tarihi 12-2013
Cilt / Sayı / Sayfa 11 / 3 / 96–101 DOI 10.4274/Jcp.11.25743
Makale Linki https://dergipark.org.tr/tr/download/article-file/904014
UAK Araştırma Alanları
Sağlık Bilimleri
Özet
Introduction: The aim of this study was to investigate the incidence of cystic fibrosis (CF) in patients with recurrent pulmonary infection, chronic diarrhea and failure to thrive having no specific diagnosis and also to investigate the demographic features, and clinic and laboratory findings of such patients.Materials and Methods: The diagnosis of CF has been established through measuring the sweat conductivity in children presenting with one or more characteristic phenotypic features of CF. A chloride concentration lower than 59 mmol/l was interpreted as negative; 60-79 as borderline and over 80 as positive. A borderline sweat test result supported with genetic mutation, nasal potential difference or elastase activity was diagnosed as atypical CF.Results: A total of 356 patients fulfilled the study criteria. Twenty (5.6%) patients were diagnosed as CF. The mean age of the patients was 19.3±18.1 months and 234 (65.7 …
Anahtar Kelimeler
Chronic diarrhea | Cystic fibrosis | Failure to thrive | Pulmonary infection | Sweat test