| Yazarlar |
Taha Ayyildiz
|
|
Ramazan Dulkadiroglu
|
|
Mevlut Yilmaz
|
|
Osman Ahmet Polat
|
Prof. Dr. Ali GÜNEŞ
Kırşehir Ahi Evran Üniversitesi |
| Özet |
| Purpose To investigate macular, Retinal Nerve Fiber Layer (RNFL) and choroidal thickness in children and adolescents with vitamin B-12 deficiency and no neurological examination finding. Methods The study group includes of thirty-three children aged 8-17 years who were brought to the Pediatric outpatient clinic with the symptoms of fatigue and forgetfulness and whose Vitamin B-12 levels were detected < 200 pg/ml. The control group was the 30 children and adolescents applied to the same policlinic with various symptoms and whose Vitamin B-12 levels were found normal. Children and adolescents with chronic systemic/ocular disease history and myopia or hyperopia more than 4 diopters were not included in both groups. Spectral Domain-Optical Coherence Tomography (SD-OCT) was used for measurements. Results Mean Macular thickness value was 261.2 +/- 17.6 in the Vitamin B-12 deficiency group and 267.7 +/- 17.4 in the control group. Mean value of Retinal Nerve Fiber Layer (RNFL) thickness was 103.5 +/- 7.5 in the Vitamin B-12 deficiency group and 104.3 +/- 8.9 in the control group. The mean values of Choroidal thickness were 360.1 +/- 59.8 and 316.9 +/- 95.4 in Vitamin B-12 deficiency and control groups, respectively. There was a statistically significant increase in choroidal thickness in Vitamin B-12 deficiency group compared to controls. Conclusion Statistically significant increase in the Choroidal thicknesses of children and adolescents with Vitamin B-12 deficiency is important in terms of shedding light on studies that will contribute to a better understanding of the relationship between vitamin B-12 and inflammation. |
| Anahtar Kelimeler |
| Vitamin B-12 deficiency, Choroid thickness, Macula, RNFL, Children, Adolescent |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | INTERNATIONAL OPHTHALMOLOGY |
| Dergi ISSN | 0165-5701 |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 70-2021 |
| Cilt No | 41 |
| Sayı | 7 |
| Sayfalar | 2399 / 2404 |
| Doi Numarası | 10.1007/s10792-021-01794-1 |
| Atıf Sayıları | |
| WoS | 3 |
| SCOPUS | 4 |
| Google Scholar | 5 |
