img
Evaluation of children with neurobrucellosis        
Yazarlar
Sinan Akbayram
Gaziantep Üniversitesi, Türkiye
Murat Doğan
Yüzüncü Yıl Üniversitesi, Türkiye
Erdal Peker
Yüzüncü Yıl Üniversitesi, Türkiye
M S Bektaş
Hüseyin Çaksen
Necmettin Erbakan Üniversitesi, Türkiye
 Mustafa Kasım KARAHOCAGİL Mustafa Kasım KARAHOCAGİL
Yüzüncü Yıl Üniversitesi, Türkiye
Özet
Background: Brucellosis is an endemic disease in many areas throughout the world. Central nervous system involvement is a serious complication of brucellosis with a ratio of 4-11% of all patients.
Aim: to describe our experience in diagnosis, treatment, and outcome of 25 pediatric patients with neurobrucellosis.
Patients and methods: This study included a review of medical records of patients who were diagnosed with neurobrucellosis between March 2001 and March 2009. Patients who had both clinical findings consistent with neurobrucellosis and positive microbiologic/serologic examinations of CSF with abnormal CSF findings were enrolled in the study.
Results: The study included 25 patients between 1 and 15 years of age (mean 8.8 years), while 15 were males and 10 were females. Most of the patients (52 %) were in the age group of 5-9 years with male predominance. The distribution of cases showed density in June and February. The most commonly presented complaints were headache, fever and sweating while the most commonly observed findings were fever and meningeal irritation signs. All patients had positive cerebrospinal fluid agglutination test for brucellosis. Four different regimens were used based on ceftriaxone, doxycycline, cotrimoxasole, streptomycin, and rifampicin. One patient died, three patients were discharged with sequel, and the remaining patients (84 %) were discharged with full recovery.
Conclusion: Clinicians, especially those providing health services in endemic areas like Turkey, should keep in mind that neurobrucellosis can be involved in patients with unexplained symptoms like memory impairment or in patients diagnosed with meningitis (Tab. 5, Fig, 2, Ref. 39). Full Text in PDF www.elis.sk.
Anahtar Kelimeler
Children | Diagnosis | Neurobrucellosis | Treatmen
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Dergi ISSN 0006-9248
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2012
Cilt No 113
Sayı 7
Sayfalar 424 / 430
Doi Numarası 10.4149/BLL_2012_096
Makale Linki http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=2966&category_id=90&option=com_virtuemart
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 4
SCOPUS 6
Google Scholar 8
Evaluation of children with neurobrucellosis

Paylaş