| Yazarlar |
Prof. Dr. Mustafa Kasım KARAHOCAGİL
Kırşehir Ahi Evran Üniversitesi |
Turan Buzgan
|
|
Hasan Irmak
|
|
Hasan Karsen
|
|
Hayrettin Akdeniz
|
|
Nevzat Akman
|
| Özet |
| This study compared the application of intramuscular recombinant hepatitis B vaccine in hemodialysis patients with the application of accelerated intradermal recombinant hepatitis B vaccine, which can be applied with one-tenth of the standard dose. Sixty seronegative patients for hepatitis B were randomly separated into two groups. Twenty mu g of the recombinant hepatitis B vaccine was intramuscularly applied at 0-, 1-, 2-, and 6-month intervals to the first group (32 cases). One more dose was applied at month 12 to those whose anti-HBs titers remained below 100 mIU/mL at month 7. The same vaccine was intradermally applied at 2 mu g dose six times with one-month intervals to the second group (28 cases). Vaccine applications were continued in those whose anti-HBs titers remained below 100 mIU/mL at month 7 until antibody titers reached above this value or until the dose number became 12. Measurements of antibody titers were repeated at month 13 in both groups. As a result, in the vaccination of hemodialysis patients against hepatitis B, the accelerated ID application of hepatitis B vaccine with a dose reduced to one-tenth is more cost-effective than the standard dose vaccination schedules. Especially for hemodialysis patients, the time has come for routine application of ID hepatitis B vaccine as an alternative vaccination method. |
| Anahtar Kelimeler |
| hepatitis B vaccination, intradermal vaccination, hemodialysis |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | Renal Failure |
| Dergi ISSN | 0886-022X |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2006 |
| Cilt No | 28 |
| Sayı | 7 |
| Sayfalar | 561 / 565 |
| Doi Numarası | 10.1080/08860220600840041 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.1080/08860220600840041 |
| Atıf Sayıları | |
| WoS | 7 |
| SCOPUS | 11 |
