Hematological Complications in 787 Cases of Acute Brucellosis in Eastern Turkey
Yazarlar (7)
Prof. Dr. Imdat Dilek Van Yüzüncü Yıl Üniversitesi, Türkiye
Arş. Gör. Ahmet Durmuş Van Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Mustafa Kasım KARAHOCAGİL Van Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Hayrettin Akdeniz Van Yüzüncü Yıl Üniversitesi, Türkiye
Hasan Karsen Van Yüzüncü Yıl Üniversitesi, Türkiye
Ali Irfan Baran Van Yüzüncü Yıl Üniversitesi, Türkiye
Ömer Evirgen Van Yüzüncü Yıl Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Turkish Journal of Medical Sciences | ||
| Dergi ISSN | 1300-0144 Dergi Bilgileri (2008) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2008 |
| Cilt / Sayı / Sayfa | 38 / 5 / 421–424 | DOI | – |
| UAK Araştırma Alanları |
Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji
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| Özet |
| Aim In this paper, we present the hematological findings of 787 cases diagnosed with acute brucellosis. Materials and Methods Records of the cases seen between 1994 and 2006 were retrospectively investigated regarding hematological changes. Results Three hundred sixty-five (46%) patients were male and 422 (54%) were female. Mean age was 32 (range: 11-78 years). Mean hematological values were as follows: Hb 12 g/dl (4-19), Htc 36%(12-56), leukocyte 6.9 x 10^ 9/L (0.5-25) and platelets 213 x 10^ 9/L (9-617). According to differential counts, 34% and 14% of patients had mononuclear cell and neutrophil dominance, respectively. Fifty-six percent of patients were found to have anemia, alone or in combination with leukopenia or thrombocytopenia. Fourteen percent of patients had thrombocytopenia, 12% leukopenia, 5% pancytopenia, 4% leukopenia+ thrombocytopenia, 0.5% acute hemolysis, and 0.1% disseminated intravascular coagulation. Restoration of thrombocytopenia and leukopenia and improvement in clinical situation were seen within one week and recovery of anemia occurred within 3-4 weeks. Conclusions Hematological complications such as anemia and leukopenia are more frequently seen in acute brucellosis cases. However, acute brucellosis should also be considered in the differential diagnosis in the presence of other hematological abnormalities such as severe thrombocytopenia, pancytopenia, acute hemolytic anemia, and disseminated intravascular coagulation. |
| Anahtar Kelimeler |
| Acute brucellosis | Hematological complications |
