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Hematological Complications in 787 Cases of Acute Brucellosis in Eastern Turkey       
Yazarlar
Imdat Dilek
Ahmet Durmus
Prof. Dr. Mustafa Kasım KARAHOCAGİL Prof. Dr. Mustafa Kasım KARAHOCAGİL
Kırşehir Ahi Evran Üniversitesi
Hayrettin Akdeniz
Hasan Karsen
Ali Irfan Baran
Oemer Evirgen
Özet
Aim: In this paper, we present the hematological findings of 787 cases diagnosed with acute brucellosis.
Materials and Methods: Records of the cases seen between 1994 and 2006 were retrospectively investigated regarding hematological changes.
Results: Three hundred sixty-five (46%) patients were male and 422 (54%) were female. Mean age was 32 (range: 11-78 years). Mean hematological values were as follows: Hb 12 g/dl (4-19), Htc 36% (12-56), leukocyte 6.9 x 10(9)/L. (0.5-25) and platelets 213 x 10(9)/L (9-617). According to differential counts, 34% and 14% of patients had mononuclear cell and neutrophil dominance, respectively. Fifty-six percent of patients were found to have anemia, alone or in combination with leukopenia or thrombocytopenia. Fourteen percent of patients had thrombocytopenia, 12% leukopenia, 5% pancytopenia, 4% leukopenia + thrombocytopenia, 0.5% acute hemolysis, and 0.1% disseminated intravascular coagulation. Restoration of thrombocytopenia and leukopenia and improvement in clinical situation were seen within one week and recovery of anemia occurred within 3-4 weeks.
Conclusions: Hematological complications such as anemia and leukopenia are more frequently seen in acute brucellosis cases. However, acute brucellosis should also be considered in the differential diagnosis in the presence of other hematological abnormalities such as severe thrombocytopenia, pancytopenia, acute hemolytic anemia, and disseminated intravascular coagulation.
Anahtar Kelimeler
Acute brucellosis | Hematological complications
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı TURKISH JOURNAL OF MEDICAL SCIENCES
Dergi ISSN 1300-0144
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe
Basım Tarihi 10-2008
Cilt No 38
Sayı 5
Sayfalar 421 / 424
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 22
SCOPUS 24
Google Scholar 48

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