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Renal Involvement in Brucella Infection        
Yazarlar
Kadir Ceylan
Prof. Dr. Mustafa Kasım KARAHOCAGİL Prof. Dr. Mustafa Kasım KARAHOCAGİL
Kırşehir Ahi Evran Üniversitesi
Yasemin Soyoral
Hayriye Sayarlioglu
Hasan Karsen
Ekrem Dogan
Hayrettin Akdeniz
Irfan Bayram
Mustafa Koesem
Reha Erkoc
Özet
OBJECTIVES To examine our patients with brucellosis and renal involvement. Although brucellae have been recovered from the urine of patients with brucellosis, renal involvement is uncommon.
METHODS The data from 15 patients (8 males and 7 females, mean age 43 +/- 18.9 years, range 16 to 80), who had been admitted to our hospital with the diagnosis of brucellosis with renal involvement from 1998 to 2006, were retrospectively evaluated.
RESULTS In almost all cases, urinalysis revealed hematuria and variable amounts of proteinuria; some of the patients had pyuria. Of the 15 patients, 14 had renal failure. The etiology of renal failure was prerenal azotemia in 1, acute tubular necrosis because of nonsteroidal anti-inflammatory drug use in 1, anuric tubulointerstitial nephritis due to rifampin use in 1, nephritis accompanied by brucellar endocarditis in 3, brucellar endocarditis and tubulointerstitial nephritis-associated vasculitis in 1, brucellar membranoproliferative glomerulonephritis in 1, and brucellar tubulointerstitial nephritis clinically in 6 patients. Hemodialysis was required in 5 patients. Chronic renal failure developed in 1 patient, 2 patients were lost to follow-up, and renal function completely recovered in 11 patients. Two patients underwent renal biopsy and membranoproliferative glomerulonephritis with intraglomerular infiltration of histiocytes was identified in 1 patient and chronic tubulointerstitial nephritis associated with vasculitis and immune complex nephritis features was identified in the other.
CONCLUSIONS In areas endemic for brucellosis, this infection can be associated with hematuria, proteinuria, and renal failure. In addition, many diverse etiologies can play a role in the renal involvement associated with Brucella infection. UROLOGY 73: 1179-1183, 2009. (C) 2009 Elsevier Inc.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı UROLOGY
Dergi ISSN 0090-4295
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce
Basım Tarihi 06-2009
Cilt No 73
Sayı 6
Sayfalar 1179 / 1183
Doi Numarası 10.1016/j.urology.2008.01.063
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S0090429508001817
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 14
SCOPUS 22
Google Scholar 43
Renal Involvement in Brucella Infection

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