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Clinical characteristics and outcome of Brucella endocarditis        
Yazarlar
Yilmaz Gunes
Mustafa Tuncer
Unal Guntekin
Serkan Akdag
Hasan Ali Gumrukcuoglu
Prof. Dr. Mustafa Kasım KARAHOCAGİL
Kırşehir Ahi Evran Üniversitesi
Hasan Ekim
Özet
Brucella endocarditis, a rare complication of brucellosis, is the main cause of death attributable to this disease. There are difficulties in the diagnosis and uncertainty regarding many aspects of the treatment of Brucella endocarditis. We retrospectively examined the clinical characteristics and outcome of patients diagnosed with Brucella endocarditis. Of the six patients diagnosed as having Brucella endocarditis, four had valvular disease, one had aortic and mitral mechanic valve prosthesis (AVR + MVR) and one had secundum type atrial septal defect. Transesophageal echocardiography showed vegetations in four patients. Blood culture grew Brucella mellitensis only in two patients. Standard agglutination tests were elevated in all patients (range 1/320-1/10240). Four patients were managed with combined antibiotherapy and surgery. One refused further treatment and one refused an operation and follow-up was lost for that patient. Two patients died during follow-up; one having had a previous AVR + MVR operation refused further treatment and the other suffering renal failure. Due to the fulminant course of the disease, treatment should be initiated when there is a clinical suspicion, even if the culture results are unknown or negative. Agglutination titres aid in the diagnosis. A combination of antibiotherapy and surgery seems to be preferable treatment modality.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı Tropical Doctor
Dergi ISSN 0049-4755
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 04-2009
Cilt No 39
Sayı 2
Sayfalar 85 / 88
Doi Numarası 10.1258/td.2008.070436
Makale Linki http://tdo.sagepub.com/lookup/doi/10.1258/td.2008.070436
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 8
SCOPUS 8
Google Scholar 25
Clinical characteristics and outcome of Brucella endocarditis

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