Asymmetric dimethylarginine levels in patients with cutaneous anthrax a laboratory analysis
Yazarlar (9)
Mahmut Sunnetcioglu Van Yüzüncü Yıl Üniversitesi, Türkiye
Zafer Mengeloglu Bolu Abant İzzet Baysal Üniversitesi, Türkiye
Ali I. Baran Van Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Mustafa Kasım KARAHOCAGİL Van Yüzüncü Yıl Üniversitesi, Türkiye
Mehmet Tosun Bolu Abant İzzet Baysal Üniversitesi, Türkiye
Abdulkadir Kucukbayrak Bolu Abant İzzet Baysal Üniversitesi, Türkiye
Mehmet R. Ceylan Van Yüzüncü Yıl Üniversitesi, Türkiye
Hayrettin Akdeniz Bolu Abant İzzet Baysal Üniversitesi, Türkiye
Cenk Aypak T. C. Sağlık Bakanlığı Ankara Diskapi Yildirim Beyazit Eğitim ve Araştirma Hastanesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Annals of Clinical Microbiology and Antimicrobials | ||
| Dergi ISSN | 1476-0711 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2014 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | – |
| Cilt / Sayı / Sayfa | 13 / 1 / 12–0 | DOI | – |
| Makale Linki | http://www.ann-clinmicrob.com/content/13/1/12 | ||
| Özet |
| BackgroundAsymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase, is considered to be associated with endothelial dysfunction. High ADMA levels have been shown to be related with disorders causing vascular inflammation such as hypertension, hypercholesterolemia, atherosclerosis, chronic heart failure, stroke and sepsis. Cutaneous anthrax (CA) is a serious infectious disease which may cause vasculitis. The aim of the study was to investigate the serum ADMA levels in patients with CA.MethodsA total of 35 serum samples of the patients with CA and 18 control sera were tested for ADMA levels using ADMA ELISA kit (Immunodiagnostik AG, Bensheim, Germany).ResultsADMA levels were found to be significantly higher in the patients group than the controls (p < 0.001). In addition, ADMA levels were found to be positively associated with sedimentation rates (R = 0.413 … |
| Anahtar Kelimeler |
| Anthrax | Dimethylarginine | Infection | Vasculitis |
