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Tuberculous and brucellosis meningitis differential diagnosis        
Yazarlar (1)
Prof. Dr. Mustafa Kasım KARAHOCAGİL Prof. Dr. Mustafa Kasım KARAHOCAGİL
Devamını Göster
Özet
Background: The Thwaites and Lancet scoring systems have been used in the rapid diagnosis of tuberculous meningitis (TBM). However, brucellar meningoencephalitis (BME) has similar characteristics with TBM. The ultimate aim of this study is to infer data to see if BME should be included in the differential diagnosis of TBM when these two systems suggest the presence of TBM.
Method: BME and TBM patients from 35 tertiary hospitals were included in this study. Overall 294 adult patients with BME and 190 patients with TBM were enrolled. All patients involved in the study had microbiological confirmation for either TBM or BME. Finally, the Thwaites and Lancet scoring systems were assessed in both groups.
Results: The Thwaites scoring system more frequently predicted BME cases (n = 292, 99.3%) compared to the TBM group (n = 182, 95.8%) (P = 0.017). According to the Lancet scoring system, the mean scores for BME and TBM were 9.43 +/- 1.71 and 11.45 +/- 3.01, respectively (P < 0.001). In addition, TBM cases were classified into "probable" category more significantly compared to BME cases, and BME cases were categorized into the "possible" category more frequently.
Conclusions: When the Thwaites or Lancet scoring systems indicate TBM, brucellar etiology should also be taken into consideration particularly in endemic countries. (C) 2015 Elsevier Ltd. All rights reserved.
Anahtar Kelimeler
Brucellosis | Diagnosis | Meningitis | Tuberculosis
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayınlanan tam makale
Dergi Adı Travel Medicine and Infectious Disease
Dergi ISSN 1477-8939 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler elsevier
Makale Dili İngilizce
Basım Tarihi 03-2015
Cilt No 13
Sayı 2
Sayfalar 185 / 191
Doi Numarası 10.1016/j.tmaid.2015.02.008
Makale Linki http://linkinghub.elsevier.com/retrieve/pii/S1477893915000356
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
WoS 16
SCOPUS 21
Google Scholar 26
Tuberculous and brucellosis meningitis differential diagnosis

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