Comparison of colistin carbapenem colistin sulbactam and colistin plus other antibacterial agents for the treatment of extremely drug resistant Acinetobacter baumannii bloodstream infections
Yazarlar (1)
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | European Journal of Clinical Microbiology and Infectious Diseases (Q2) | ||
| Dergi ISSN | 0934-9723 Dergi Bilgileri (2014) | ||
| Dergi Tarandığı Indeksler | SSCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2014 |
| Cilt / Sayı / Sayfa | 33 / 8 / 1311–1322 | DOI | 10.1007/s10096-014-2070-6 |
| Makale Linki | http://link.springer.com/10.1007/s10096-014-2070-6 | ||
| UAK Araştırma Alanları |
Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji
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| Özet |
| The purpose of this investigation was to compare the efficacy of colistin-based therapies in extremely drug-resistant Acinetobacter spp. bloodstream infections (XDR-ABSI). A retrospective study was conducted in 27 tertiary-care centers from January 2009 to August 2012. The primary end-point was 14-day survival, and the secondary end-points were clinical and microbiological outcomes. Thirty-six and 214 patients [102 (47.7 %): colistin–carbapenem (CC), 69 (32.2 %): colistin–sulbactam (CS), and 43 (20.1 %: tigecycline): colistin with other agent (CO)] received colistin monotherapy and colistin-based combinations, respectively. Rates of complete response/cure and 14-day survival were relatively higher, and microbiological eradication was significantly higher in the combination group. Also, the in-hospital mortality rate was significantly lower in the combination group. No significant difference was found in the … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 149 |
| Scopus | 173 |
| Google Scholar | 253 |