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Fibromyalgia Frequency in Hepatitis B Carriers     
Yazarlar
Burhan Adak
İstanbul Medipol Üniversitesi, Türkiye
İbrahim Tekeoğlu
Sakarya Üniversitesi, Türkiye
Levent Ediz
Yüzüncü Yıl Üniversitesi, Türkiye
Mustafa Budancamanak
Turan Buzgan
Prof. Dr. Mustafa Kasım KARAHOCAGİL Prof. Dr. Mustafa Kasım KARAHOCAGİL
Yüzüncü Yıl Üniversitesi, Türkiye
Adnan Demirel
Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Özet
Background: Fibromyalgia (FM) is characterized by diffuse musculoskeletal pain, fatigue, morning stiffness, and sleep disturbance. Chronic viral infections may trigger FM symptoms.
Objectives: In this study, we aimed to evaluate whether there was an association between HBsAg seropositivity and fibromyalgia syndrome.
Methods: Fifty hepatitis B carriers (HBsAg positivity and anti-HBs negativity in sera for at least 6 months) and 50 age- and sex-matched HbsAg-negative control subjects were enrolled in this study. The hepatitis B carriers with normal or slightly elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were recruited from the infectious diseases outpatient clinic and the control group was recruited from the physical medicine and rehabilitation outpatient clinic. The relationship between groups was calculated by independent Student t test, chi-squared test, and Fisher exact test for comparing proportions. Alpha criterion for significance was set at P < 0.05.
Results: There was no statistically significant difference between the groups according to sex, mean age, body mass index, serum ALT, and AST levels (P > 0.05). FM syndrome and FM-associated symptoms were much more prevalent in the hepatitis B group (P < 0.001).
Conclusion: The present study suggests that chronic hepatitis B carriage appears to increase the risk of FM and many of the typically associated symptoms. Whether this association is related to altered liver function, viral infection, concerns associated with chronic disease, or other factors, physicians should be aware of this apparent association.
Anahtar Kelimeler
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı JCR: Journal of Clinical Rheumatology
Dergi ISSN 1076-1608
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 01-2005
Cilt No 11
Sayı 3
Sayfalar 157 / 159
Doi Numarası 10.1097/01.rhu.0000165291.91623.5c
Makale Linki http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00124743-200506000-00008
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Fibromyalgia Frequency in Hepatitis B Carriers

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