| Yazarlar |
Burhan Adak
İstanbul Medipol Üniversitesi, Türkiye |
|
İbrahim Tekeoğlu
Sakarya Üniversitesi, Türkiye |
|
Levent Ediz
Yüzüncü Yıl Üniversitesi, Türkiye |
|
Mustafa Budancamanak
|
|
Turan Buzgan
|
Mustafa Kasım KARAHOCAGİL
Yüzüncü Yıl Üniversitesi, Türkiye |
|
Adnan Demirel
Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye |
| Özet |
| Background: Fibromyalgia (FM) is characterized by diffuse musculoskeletal pain, fatigue, morning stiffness, and sleep disturbance. Chronic viral infections may trigger FM symptoms. Objectives: In this study, we aimed to evaluate whether there was an association between HBsAg seropositivity and fibromyalgia syndrome. Methods: Fifty hepatitis B carriers (HBsAg positivity and anti-HBs negativity in sera for at least 6 months) and 50 age- and sex-matched HbsAg-negative control subjects were enrolled in this study. The hepatitis B carriers with normal or slightly elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were recruited from the infectious diseases outpatient clinic and the control group was recruited from the physical medicine and rehabilitation outpatient clinic. The relationship between groups was calculated by independent Student t test, chi-squared test, and Fisher exact test for comparing proportions. Alpha criterion for significance was set at P < 0.05. Results: There was no statistically significant difference between the groups according to sex, mean age, body mass index, serum ALT, and AST levels (P > 0.05). FM syndrome and FM-associated symptoms were much more prevalent in the hepatitis B group (P < 0.001). Conclusion: The present study suggests that chronic hepatitis B carriage appears to increase the risk of FM and many of the typically associated symptoms. Whether this association is related to altered liver function, viral infection, concerns associated with chronic disease, or other factors, physicians should be aware of this apparent association. |
| Anahtar Kelimeler |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | JCR: Journal of Clinical Rheumatology |
| Dergi ISSN | 1076-1608 |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2005 |
| Cilt No | 11 |
| Sayı | 3 |
| Sayfalar | 157 / 159 |
| Doi Numarası | 10.1097/01.rhu.0000165291.91623.5c |
| Makale Linki | http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00124743-200506000-00008 |
| Atıf Sayıları |
