A Comparison of the Effects of Esmolol and Dexmedetomidine on theClinical Course and Cost for Controlled Hypotensive Anaesthesia
   
Yazarlar (4)
Doç. Dr. Zeynel Abidin ERBESLER Erciş Devlet Hastanesi, Türkiye
Nurten Bakan T.C. Sağlık Bakanlığı,, Türkiye
Gülşah Yilmaz Karaören T.C. Sağlık Bakanlığı,, Türkiye
Muhammet Ali Erkmen T.C. Sağlık Bakanlığı,, Türkiye
Makale Türü Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Turk Anesteziyoloji Ve Reanimasyon Dernegi Dergisi
Dergi ISSN 1304-0871
Dergi Tarandığı Indeksler ESCI: Emerging Sources Citation Index
Makale Dili İngilizce Basım Tarihi 10-2013
Cilt / Sayı / Sayfa 41 / 5 / 156–161 DOI 10.5152/TJAR.2013.36
Makale Linki http://www.jtaics.org/jvi.aspx?pdir=tardplng=engun=TARD-86570look4=
Özet
Objective To compare the effects of esmolol (β-blocker) and dexmedetomidine (α-2-agonist) on patients’ clinical course and cost of application of controlled hypotension during middle-ear surgery. Methods Fifty ASA I–II patients scheduled for tympanomastoidectomy were enrolled in the study and were randomized into two groups. Bispectral Index (BIS) and neuromuscular monitoring (TOF GUARD-SX) were applied to all patients. In group E (n=25), 0.5 mg kg−1 min−1 esmolol was infused over 1 min before induction and titrated over a range of 10–200 μg kg−1 min−1; in group D (n=25), 0.5 μg kg−1 dexmedetomidine was infused over 10 minutes before induction, and then titrated over a range of 0.2–0.7 μg kg−1 hr−1 to maintain mean arterial pressure (MAP) between 55 and 65 mmHg and BIS 40–50 after induction. In both groups, 0.25 μg kg−1 min−1 remifentanil infusion was used for anaesthesia maintenance …
Anahtar Kelimeler
Anesthesia | Controlled hypotension | Dexmedetomidine | Esmolol | Middle ear surgery