| Makale Türü | Özgün Makale (ESCI dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Turk Anesteziyoloji Ve Reanimasyon Dernegi Dergisi | ||
| Dergi ISSN | 1304-0871 | ||
| Dergi Tarandığı Indeksler | ESCI: Emerging Sources Citation Index | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2013 |
| Cilt / Sayı / Sayfa | 41 / 5 / 156–161 | DOI | 10.5152/TJAR.2013.36 |
| Makale Linki | http://www.jtaics.org/jvi.aspx?pdir=tardplng=engun=TARD-86570look4= | ||
| Özet |
| Objective To compare the effects of esmolol (β-blocker) and dexmedetomidine (α-2-agonist) on patients’ clinical course and cost of application of controlled hypotension during middle-ear surgery. Methods Fifty ASA I–II patients scheduled for tympanomastoidectomy were enrolled in the study and were randomized into two groups. Bispectral Index (BIS) and neuromuscular monitoring (TOF GUARD-SX) were applied to all patients. In group E (n=25), 0.5 mg kg−1 min−1 esmolol was infused over 1 min before induction and titrated over a range of 10–200 μg kg−1 min−1; in group D (n=25), 0.5 μg kg−1 dexmedetomidine was infused over 10 minutes before induction, and then titrated over a range of 0.2–0.7 μg kg−1 hr−1 to maintain mean arterial pressure (MAP) between 55 and 65 mmHg and BIS 40–50 after induction. In both groups, 0.25 μg kg−1 min−1 remifentanil infusion was used for anaesthesia maintenance … |
| Anahtar Kelimeler |
| Anesthesia | Controlled hypotension | Dexmedetomidine | Esmolol | Middle ear surgery |