The effect of edaravone on ischemia reperfusion injury in rat ovary
Yazarlar (5)
Prof. Dr. Mustafa KARA Bozok Üniversitesi, Türkiye
Prof. Dr. Yusuf Kenan DAĞLIOĞLU Çukurova Üniversitesi, Türkiye
Kuyucu Yurdun
Abdullah Tuli Çukurova Üniversitesi, Türkiye
Özgül Tap Çukurova Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | ||
| Dergi ISSN | 0301-2115 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2012 |
| Cilt / Sayı / Sayfa | 162 / 2 / 197–202 | DOI | 10.1016/j.ejogrb.2012.02.026 |
| Özet |
| OBJECTIVE The aim of this study was to investigate the effect of edaravone on experimentally induced ovarian torsion/detorsion ischemia/reperfusion (I/R) injury. STUDY DESIGN Forty-six female adult Wistar-Albino rats were utilized to create five groups: In group 1, only 5mg/kg edaravone was given and ovary torsion was not performed. In group 2, torsion was not performed and no drug was given. In group 3, vehicle was given and torsion/detorsion was performed. In group 4, 1mg/kg edaravone was given and torsion/detorsion was performed. In group 5, edaravone; 5mg/kg drug was administered and torsion/detorsion was performed. Right ovarian torsion was simulated for a 3-h period of ischemia and a 1-h reperfusion period. Right ovaries were then surgically extirpated in all groups. In ovarian tissue samples malondialdehyde (MDA) levels and activity of superoxide dismutase were studied. Microscopic ovarian … |
| Anahtar Kelimeler |
| Edaravone | Ovarian torsion | Rat torsion model | Ischemia-reperfusion |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 62 |
| Web of Science | 26 |