Impacts of β-estradiol on intestinal injury in newborn rats
Yazarlar (8)
Hasan Kılıçdağ Acıbadem Üniversitesi, Türkiye
Prof. Dr. Yusuf Kenan DAĞLIOĞLU Çukurova Üniversitesi, Türkiye
Leman Sencar Gündoğdu Çukurova Üniversitesi, Türkiye
Şeyda Erdoğan Çukurova Üniversitesi, Türkiye
Suzan Zorludemir Çukurova Üniversitesi, Türkiye
Sait Polat Çukurova Üniversitesi, Türkiye
Emine Kılıç Bağır Çukurova Üniversitesi, Türkiye
Gülfidan Coşkun Çukurova Üniversitesi, Türkiye
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale) | ||
| Dergi Adı | The Journal of Maternal-Fetal Neonatal Medicine (Q3) | ||
| Dergi ISSN | 1476-7058 Dergi Bilgileri (2015) | ||
| Dergi Tarandığı Indeksler | SSCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 08-2015 |
| Cilt / Sayı / Sayfa | 29 / 12 / 1935–1940 | DOI | 10.3109/14767058.2015.1068286 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.3109/14767058.2015.1068286 | ||
| UAK Araştırma Alanları |
Tıbbi Mikrobiyoloji
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| Özet |
| Objective: Necrotizing enterocolitis has been investigated and debated extensively in recent years; however, there is still no effective treatment. The aim of this study was thus to examine the effects of β-estradiol on intestinal injury in rats.Methods: Twenty-four newborn female rat pups were divided into three groups. In group 1 (sham), hypoxia–re-oxygenation was not performed. In group 2 (saline), the rats were injected with saline after hypoxia–re-oxygenation, and the process was repeated for 5 d. In group 3 (β-estradiol treatment), the rats were subjected to hypoxia–re-oxygenation and then given β-estradiol intraperitoneally once a day for 5 d. After these procedures, the terminal ileum was removed for analysis.Results: Statistically significant differences in histological grades were found between groups 1 and 2 (p = 0.000), groups 1 and 3 (p = 0.028), and groups 2 and 3 (p = 0.021). There were also … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 2 |